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Application progress of IVIM imaging technology in evaluating physiological and pathological status of skeletal muscle
TIAN Dijiao  WAN Bing  LIU Yue  ZHANG Dewen  WANG Wen  HUANG Yitian 

Cite this article as: TIAN D J, WAN B, LIU Y, et al. Application progress of IVIM imaging technology in evaluating physiological and pathological status of skeletal muscle[J]. Chin J Magn Reson Imaging, 2024, 15(10): 222-227, 233. DOI:10.12015/issn.1674-8034.2024.10.038.


[Abstract] Skeletal muscle is an important motor organ in human body, and its function is closely related to human daily activities. However, the morphological manifestations of skeletal muscle lesions are lagging behind the microscopic pathological changes. In recent years, the evaluation of water molecule movement and capillary perfusion information of skeletal muscle from a microscopic perspective has gradually become a hot spot in clinical research. Intravoxel incoherent motion (IVIM) is a dual-exponential MR diffusion imaging technique, which uses the characteristics of water molecule diffusion and capillary network circulation to provide us with important information related to tissue function, including true diffusion coefficient (D), false diffusion coefficient (D*) and perfusion fraction (F), etc. This imaging mechanism coincides with the physiological characteristics of skeletal muscle. Based on the principles and parameters of IVIM imaging, combined with the physiological characteristics of skeletal muscle and the changes in aging and diseases, this paper summarizes the application research of IVIM technology in three aspects: physiological aging and degeneration of skeletal muscle, evaluation of skeletal muscle injury/repair in different exercise states, differential diagnosis of common muscle diseases and functional evaluation, and discusses the parameter setting, clinical significance and application limitations in related research, aiming at providing more reference value for the application of IVIM technology in skeletal muscle imaging.
[Keywords] intravoxel incoherent movement；skeletal muscle；functional magnetic resonance imaging；magnetic resonance imaging；water molecule dispersion；microcirculatory perfusion

TIAN Dijiao   WAN Bing*   LIU Yue   ZHANG Dewen   WANG Wen   HUANG Yitian  

Department of Radiology, Renhe Hospital affiliated to China Three Gorges University, Yichang 443001

Corresponding author: WAN B, E-mail: 23130293@qq.com

Conflicts of interest   None.

Received  2024-06-13
Accepted  2024-10-10
DOI: 10.12015/issn.1674-8034.2024.10.038
Cite this article as: TIAN D J, WAN B, LIU Y, et al. Application progress of IVIM imaging technology in evaluating physiological and pathological status of skeletal muscle[J]. Chin J Magn Reson Imaging, 2024, 15(10): 222-227, 233. DOI:10.12015/issn.1674-8034.2024.10.038.

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