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Advances in behavior and imaging studies of cognitive flexibility changes in neurodegenerative disease
CAO Xinyu  YU Ying  HU Bo  YAN Linfeng  CUI Guangbin 

Cite this article as: CAO X Y, YU Y, HU B, et al. Advances in behavior and imaging studies of cognitive flexibility changes in neurodegenerative disease[J]. Chin J Magn Reson Imaging, 2024, 15(11): 148-152. DOI:10.12015/issn.1674-8034.2024.11.023.


[Abstract] Cognitive flexibility refers to the individual to be able to quickly adapt to changing circumstances, and in the process to switch quickly thinking mode and the ability of adaptation in response. In neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis can be observed in the patients with flexibly shift their own mental processes and behavior to adapt the environment change ability dropped significantly (i.e, impaired cognitive flexibility). This article aims to review and summarize the previous research progress on behavioral assessment methods and imaging studies of cognitive flexibility in neurodegenerative diseases, so as to provide a theoretical basis for the diagnosis and treatment of cognitive flexibility decline caused by neurodegenerative diseases.
[Keywords] cognitive flexibility；neurodegenerative diseases；magnetic resonance imaging；Alzheimer's disease；Parkinson's disease；Wisconsin Card Sorting Test

CAO Xinyu1, 2   YU Ying2   HU Bo2   YAN Linfeng2   CUI Guangbin2*  

1 Medical School of Yan'an University, Yan'an716000, China

2 Department of Radiology, Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Air Force Medical University, Xi'an710038, China

Corresponding author: CUI G B, E-mail: cgbtd@126.com

Conflicts of interest   None.

Received  2024-06-27
Accepted  2024-10-10
DOI: 10.12015/issn.1674-8034.2024.11.023
Cite this article as: CAO X Y, YU Y, HU B, et al. Advances in behavior and imaging studies of cognitive flexibility changes in neurodegenerative disease[J]. Chin J Magn Reson Imaging, 2024, 15(11): 148-152. DOI:10.12015/issn.1674-8034.2024.11.023.

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