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• Review •
The progress of brain structural and functional magnetic resonance imaging in patients with obstructive sleep apnea
SUN Liqiang  LI Lin  HU Jing  LIU Liying  CUI Kaige  YANG Jiping  JIA Juan  YU Jiaqi 

Cite this article as: SUN L Q, LI L, HU J, et al. The progress of brain structural and functional magnetic resonance imaging in patients with obstructive sleep apnea[J]. Chin J Magn Reson Imaging, 2024, 15(11): 160-168. DOI:10.12015/issn.1674-8034.2024.11.025.


[Abstract] Obstructive sleep apnea (OSA) is the most common sleep disorder with abnormal brain structure and function, leading to a complication of cognitive impairment. In recent years, MRI has been flourishing, including voxel based morphometry (VBM), diffusion tensor imaging (DTI), diffusion tensor imaging analysis along the perivascular space (DTI-ALPS), diffusion kurtosis imaging (DKI), resting state functional magnetic resonance imaging (rs-fMRI), arterial spin labeling (ASL), magnetic resonance spectroscopy (MRS). Especially newly emerging DTI-ALPS and DKI techniques have provided a more novel perspective and broader field of view. DTI-ALPS can evaluate the function of the cerebral lymphatic system non-invasively and reveal the mechanism of lymphatic metabolism disorders in OSA patients, which provide a new perspective for the pathological and physiological mechanism of OSA patients, and provide new ideas for the improvement of treatment plans. DKI could demonstrate microstructural abnormalities of the brain more sensitively before changes might be found with conventional imaging, that provide a basis for earlier diagnosis and treatment of OSA patients. This article reviews the progress of cerebral structural and functional magnetic resonance imaging of OSA patients in recent years, aiming to reveal their neuroimaging changes and pathophysiological mechanisms, and to provide basis for early diagnosis, treatment, and improvement of treatment plans for OSA patients.
[Keywords] obstructive sleep apnea；magnetic resonance imaging；resting state functional magnetic resonance imaging；diffusion tensor imaging analysis along the perivascular space；diffusion kurtosis imaging；glymphatic system

SUN Liqiang1   LI Lin2   HU Jing3   LIU Liying3   CUI Kaige3   YANG Jiping3*   JIA Juan3   YU Jiaqi3  

1 Department of Medical Imaging, Hebei General Hospital, Shijiazhuang050051, China

2 Department of Otolaryngology, Hebei General Hospital, Shijiazhuang050051, China

3 Department of Medical Imaging, the Second Hospital of Hebei Medical University, Shijiazhuang050000, China

Corresponding author: YANG J P, E-mail: ran0511@sina.com

Conflicts of interest   None.

Received  2024-07-26
Accepted  2024-11-08
DOI: 10.12015/issn.1674-8034.2024.11.025
Cite this article as: SUN L Q, LI L, HU J, et al. The progress of brain structural and functional magnetic resonance imaging in patients with obstructive sleep apnea[J]. Chin J Magn Reson Imaging, 2024, 15(11): 160-168. DOI:10.12015/issn.1674-8034.2024.11.025.

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