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Research progress of free water diffusion tensor imaging in neurodegenerative diseases
SUN Xuan  WANG Bingbing  BAI Yan  WU Yaping  WANG Meiyun 

Cite this article as: SUN X, WANG B B, BAI Y, et al. Research progress of free water diffusion tensor imaging in neurodegenerative diseases[J]. Chin J Magn Reson Imaging, 2024, 15(12): 171-175. DOI:10.12015/issn.1674-8034.2024.12.026.


[Abstract] As people live longer, the prevalence of neurodegenerative diseases with aging as a major risk factor is also increasing, which leads to serious medical and socioeconomic problems. Diffusion tensor imaging (DTI) is a magnetic resonance imaging technique that can noninvasively detect brain microstructure changes, and is widely used in clinical and research of neurodegenerative diseases. However, due to the partial volume effect and other reasons, the accuracy of DTI measurement may be affected. Free water diffusion tensor imaging (FW-DTI) not only makes up for the above deficiencies to a large extent, but also enhances the sensitivity of standard DTI indicators to neurodegenerative diseases. This article will review the current research progress of FW-DTI technology in neurodegenerative diseases, in order to provide new ideas for future research.
[Keywords] neurodegenerative diseases；Alzheimer's disease；Parkinson's disease；free water diffusion tensor imaging；magnetic resonance imaging

SUN Xuan1, 2   WANG Bingbing2   BAI Yan2, 3   WU Yaping2, 3   WANG Meiyun2, 3*  

1 Department of Medical Imaging, Zhengzhou University People's Hospital, Zhengzhou450003, China

2 Department of Medical Imaging, Henan Provincial People's Hospital, Zhengzhou450003, China

3 Biomedical Research Institute, Henan Academy of Sciences, Zhengzhou450046, China

Corresponding author: WANG M Y, E-mail: mywang@zzu.edu.cn

Conflicts of interest   None.

Received  2024-09-04
Accepted  2024-12-10
DOI: 10.12015/issn.1674-8034.2024.12.026
Cite this article as: SUN X, WANG B B, BAI Y, et al. Research progress of free water diffusion tensor imaging in neurodegenerative diseases[J]. Chin J Magn Reson Imaging, 2024, 15(12): 171-175. DOI:10.12015/issn.1674-8034.2024.12.026.

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