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Research progress of multimodal MRI in tremor-dominant Parkinson's disease
HUANG Junlin  FAN Wanfeng  ZU Hanyu  WANG Yutang  JIANG Xingyue 

Cite this article as: HUANG J L, FAN W F, ZU H Y, et al. Research progress of multimodal MRI in tremor-dominant Parkinson's disease[J]. Chin J Magn Reson Imaging, 2024, 15(12): 181-186. DOI:10.12015/issn.1674-8034.2024.12.028.


[Abstract] Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder, typified by resting tremors, bradykinesia, rigidity, and postural instability. The tremor-dominant (TD) subtype of PD is characterized mainly by limb tremors, which severely impact the quality of life in advanced TD-PD patients. Advances in magnetic resonance imaging (MRI) techniques have provided several non-invasive scientific methods for studying brain structure and function in TD-PD. This paper discusses the structural and functional aspects of the brain, reviewing the progress in multimodal MRI techniques such as three-dimensional T1-weighted imaging (3D-T1WI), diffusion tensor imaging (DTI), blood oxygenation level-dependent (BOLD) imaging, susceptibility-weighted imaging (SWI), magnetic resonance spectroscopy (MRS), and neuromelanin-sensitive MRI (NM-MRI) in TD-PD patients, offering new insights for future research.
[Keywords] Parkinson's disease；tremor；magnetic resonance imaging；structural magnetic resonance imaging；functional magnetic resonance imaging

HUANG Junlin1, 2   FAN Wanfeng1   ZU Hanyu1   WANG Yutang2   JIANG Xingyue1, 2*  

1 Department of Radiology, Binzhou Medical University Hospital, Binzhou256600, China

2 School of Medical Imaging, Binzhou Medical University, Yantai264003, China

Corresponding author: JIANG X Y, E-mail: xyjiang188@sina.com

Conflicts of interest   None.

Received  2024-09-18
Accepted  2024-12-10
DOI: 10.12015/issn.1674-8034.2024.12.028
Cite this article as: HUANG J L, FAN W F, ZU H Y, et al. Research progress of multimodal MRI in tremor-dominant Parkinson's disease[J]. Chin J Magn Reson Imaging, 2024, 15(12): 181-186. DOI:10.12015/issn.1674-8034.2024.12.028.

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