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• Review •
Advances in MRI of the glymphatic system in brain tumors
LIANG Xue  ZHANG Xin  ZHANG Bing 

Cite this article as: LIANG X, ZHANG X, ZHANG B. Advances in MRI of the glymphatic system in brain tumors[J]. Chin J Magn Reson Imaging, 2024, 15(12): 206-211. DOI:10.12015/issn.1674-8034.2024.12.032.


[Abstract] The glymphatic system (GS), a pivotal mechanism for waste clearance in the central nervous system, has emerged as a significant discovery in the realm of neuroscience in recent years. Advancements in MRI technology have enabled the non-invasive observation and investigation of GS's structure and function in vivo. While the dysfunction of the GS has been related to a myriad of neurological conditions, particularly within the spectrum of neurodegenerative diseases, its role in the context of brain tumors has been less extensively explored. This review comprehensively summarizes the anatomy and physiology of the GS, identifies factors that can damage it, and introduces principal MRI-based assessment methods. It explores the role of the GS in the pathological changes associated with brain tumors and discusses its potential applications in the diagnosis and treatment of these tumors, aiming to provide novel perspectives and methodologies for research in this field.
[Keywords] glymphatic system；magnetic resonance imaging；brain tumors；therapy；pathophysiology

LIANG Xue1, 2   ZHANG Xin2   ZHANG Bing1, 2*  

1 Department of Radiology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing210008, China

2 Department of Radiology, the Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing210008, China

Corresponding author: ZHANG B, E-mail: zhangbing_nanjing@nju.edu.cn

Conflicts of interest   None.

Received  2024-08-09
Accepted  2024-12-10
DOI: 10.12015/issn.1674-8034.2024.12.032
Cite this article as: LIANG X, ZHANG X, ZHANG B. Advances in MRI of the glymphatic system in brain tumors[J]. Chin J Magn Reson Imaging, 2024, 15(12): 206-211. DOI:10.12015/issn.1674-8034.2024.12.032.

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