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Recent progress and prospect of multimodal magnetic resonance imaging in Gilles de la Tourette syndrome
LIU Xiao  GUO Xiangfa  LI Xiaoling  WANG Yang  GAO Shenglan  WEI Zeyi 

Cite this article as: LIU X, GUO X F, LI X L, et al. Recent progress and prospect of multimodal magnetic resonance imaging in Gilles de la Tourette syndrome[J]. Chin J Magn Reson Imaging, 2025, 16(1): 175-180, 192. DOI:10.12015/issn.1674-8034.2025.01.028.


[Abstract] Gilles de la Tourette syndrome (GTS) is a category of childhood neurodevelopmental disorders, with a few cases extending to adulthood. Typical signs of GTS include involuntary movement and vocal tic, often accompanied by attention deficit hyperactivity disorder, which seriously affects the quality of life of patients. The onset of GTS is associated with abnormal circuit function of cortico-striato-thalamo-cortical (CSTC). At present, the research on the mechanism of GTS pathogenesis, premonitory impulse, tic degree and social cognition based on MRI has gradually become a hot topic in the industry. Structural and functional MRI can reveal the activation and network changes of GTS sensory, motor, emotional, cognitive and other related brain areas. The author has reviewed recent literature on various modalities of imaging, including voxel-based morphometry (VBM), diffusion tensor imaging (DTI), functional MRI (fMRI), and magnetic resonance spectroscopy (MRS), and summarized the findings to help with early disease identification and further exploration.
[Keywords] Gilles de la Tourette syndrome；magnetic resonance imaging；structural magnetic resonance imaging；diffusion tensor imaging；functional magnetic resonance imaging；magnetic resonance spectroscopy

LIU Xiao1, 2   GUO Xiangfa3   LI Xiaoling4*   WANG Yang4   GAO Shenglan5   WEI Zeyi3  

1 Department of Pediatrics, the First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150040, China

2 Graduate School, Heilongjiang University of Chinese Medicine, Harbin 150040, China

3 Department of Medical Imaging, the Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150001, China

4 Department of CT Magnetic Resonance, the First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150040, China

5 Department of Radiology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China

Corresponding author: LI X L, E-mail: lixiaoling1525@163.com

Conflicts of interest   None.

Received  2024-09-03
Accepted  2025-01-10
DOI: 10.12015/issn.1674-8034.2025.01.028
Cite this article as: LIU X, GUO X F, LI X L, et al. Recent progress and prospect of multimodal magnetic resonance imaging in Gilles de la Tourette syndrome[J]. Chin J Magn Reson Imaging, 2025, 16(1): 175-180, 192. DOI:10.12015/issn.1674-8034.2025.01.028.

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