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• Clinical Article •
Comparative study on the display effect of two three-dimensional magnetic resonance neuroimaging techniques on mandibular nerve extracranial segment in patients with nasopharyngeal carcinoma
LUO Jiangjing  XU Lieyin  HU Yufang  TANG Yanyun 

Cite this article as: LUO J J, XU L Y, HU Y F, et al. Comparative study on the display effect of two three-dimensional magnetic resonance neuroimaging techniques on mandibular nerve extracranial segment in patients with nasopharyngeal carcinoma[J]. Chin J Magn Reson Imaging, 2025, 16(3): 38-43. DOI:10.12015/issn.1674-8034.2025.03.006.


[Abstract] Objective To compare the feasibility and value of three-dimensional double echo steady state (3D-DESS) sequence and three-dimensional flip-angle evolution short-tau inversion (3D-SPACE-STIR) sequence in the display of mandibular nerve extracranial segment in patients with nasopharyngeal carcinoma.Materials and Methods The image data of 36 patients with nasopharyngeal carcinoma meeting the inclusion and exclusion criteria were retrospectively analyzed, with a total of 72 mandibular nerves. The paired sample t test and paired sample Wilcoxon sign rank sum test were used to compare the subjective scores and objective parameters of the display quality of the two sequences, including the signal intensity ratio (SIR), signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of the images. Paired Chi-square test was used to compare the mandibular nerve involvement between the two sequences in nasopharyngeal carcinoma.Results Both 3D-DESS and 3D-SPACE-STIR sequences had a higher display rate of mandibular nerve, and the subjective quality scores of both showed a good performance, which were 4 and 3 points, respectively, with no statistical significance (P = 0.052); 3D-SPACE-STIR sequence SIRN/M was better than 3D-DESS sequence, 3.55 and 1.40, respectively, and the difference was statistically significant (P < 0.001). SNRM of 3D-DESS sequence was better than that of 3D-SPACE-STIR sequence (13.68 and 8.00, respectively), and the difference was statistically significant (P = 0.002). A total of 24 mandibular nerves were involved by tumors. 3D-DESS sequences showed better relationship between nerves and tumors (95.83% vs. 12.50%), nerve continuity (87.50% vs. 37.50%) and nerve morphology (70.83% vs. 29.17%) of tumor segments than 3D-SPACE-STIR sequences, and the differences were statistically significant (P < 0.001, P < 0.001, P = 0.004). The 3D-SPACE-STIR sequence showed that the nerve thickening in non-tumor segment was better than that in 3D-DESS sequence (70.83% vs. 41.67%), and the difference was statistically significant (P = 0.042).Conclusions 3D-DESS and 3D-SPACE-STIR have similar display rates on the extracranial segment of mandibular nerve, but 3D-DESS is based on better resolution of the relationship between nerve and surrounding structure and low field of view value, and its clinical application is worthy of promotion.
[Keywords] three-dimensional double echo steady state；three-dimensional flip-angle evolution short-tau inversion；mandibular nerve；magnetic resonance imaging；nasopharynx cancer；cranial nerves

LUO Jiangjing   XU Lieyin*   HU Yufang   TANG Yanyun  

Department of Radiology, the Affiliated Hospital of Guilin Medical College, Guiliu 541001, China

Corresponding author: XU L Y, E-mail: xlygxgl@163.com

Conflicts of interest   None.

Received  2024-08-27
Accepted  2025-03-10
DOI: 10.12015/issn.1674-8034.2025.03.006
Cite this article as: LUO J J, XU L Y, HU Y F, et al. Comparative study on the display effect of two three-dimensional magnetic resonance neuroimaging techniques on mandibular nerve extracranial segment in patients with nasopharyngeal carcinoma[J]. Chin J Magn Reson Imaging, 2025, 16(3): 38-43. DOI:10.12015/issn.1674-8034.2025.03.006.

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