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Advances in multimodal MRI of acupuncture for post-stroke depression
LIU Keyan  YANG Keqin  ZHAO Bin  WANG Gege 

Cite this article as: LIU K Y, YANG K Q, ZHAO B, et al. Advances in multimodal MRI of acupuncture for post-stroke depression[J]. Chin J Magn Reson Imaging, 2025, 16(3): 109-115. DOI:10.12015/issn.1674-8034.2025.03.018.


[Abstract] Post-stroke depression (PSD) is a mood disorder syndrome characterized by emotional depression and loss of interest, which is a common complication after stroke. Acupuncture treatment for PSD has proven effective in improving depressive symptoms, but its mechanism requires further investigation. Multimodal MRI has the advantage of accurately locating and observing the immediate effects of abnormal brain regions in PSD, providing effective evidence and visual support for the study of the brain mechanism and efficacy evaluation of acupuncture treatment for PSD. This review will summarize the literature on acupuncture treatment for PSD from the perspectives of resting-state functional magnetic resonance imaging, diffusion tensor imaging, voxel-based morphometry, and magnetic resonance spectroscopy. By analyzing cerebral structural changes, functional connectivity, neuronal activity, white matter fiber tract integrity, and gray matter structure related to PSD, we aim to investigate the mechanisms underlying acupuncture therapy and provide new insights into acupuncture treatment for PSD.
[Keywords] acupuncture；post stroke depression；magnetic resonance imaging；resting-state functional magnetic resonance imaging；diffusion tensor imaging；voxel-based morphometry；magnetic resonance spectroscopy

LIU Keyan1   YANG Keqin2   ZHAO Bin2*   WANG Gege1  

1 Graduate School of Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China

2 Rehabilitation Centre, Heilongjiang University of Chinese Medicine Affiliated Second Hospital Rehabilitation Center, Harbin 150001, China

Corresponding author: ZHAO B, E-mail: 521zhaobin@163.com

Conflicts of interest   None.

Received  2024-10-30
Accepted  2025-03-10
DOI: 10.12015/issn.1674-8034.2025.03.018
Cite this article as: LIU K Y, YANG K Q, ZHAO B, et al. Advances in multimodal MRI of acupuncture for post-stroke depression[J]. Chin J Magn Reson Imaging, 2025, 16(3): 109-115. DOI:10.12015/issn.1674-8034.2025.03.018.

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