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Research progress of Functional Connectivity in self-limited epilepsy with centrotemporal spikes
GU Xiaoyu  ZHANG Jiaren  SONG Linfeng  WANG Junjun  JIANG Lin 

Cite this article as: GU X Y, ZHANG J R, SONG L F, et al. Research progress of Functional Connectivity in self-limited epilepsy with centrotemporal spikes[J]. Chin J Magn Reson Imaging, 2025, 16(4): 114-119, 138. DOI:10.12015/issn.1674-8034.2025.04.018.


[Abstract] Self-limited epilepsy with centrotemporal spikes (SeLECTS) is the most common age-dependent, self-limited focal epilepsy of childhood, characterised by interictal centrotemporal (Rolandic) spikes on the EEG. Although SeLECTS is considered self-limiting, some children have cognitive deficits in language, reading, visuospatial, executive function and attention. These deficits may be related to abnormalities in functional connectivity (FC), which can be paradoxically increased and decreased in different brain regions at the same time. This paper briefly introduces common functional connectivity research methods, summarises the strengths and weaknesses of these methods, and also summarises the research progress of FC in SeLECTS over the past years, with the aim of exploring the potential of FC as a biomarker for predicting cognitive and seizure outcomes.
[Keywords] self-limited epilepsy with centrotemporal spikes；Rolandic epilepsy；magnetic resonance imaging；functional magnetic resonance imaging；brain network；functional connectivity

GU Xiaoyu   ZHANG Jiaren   SONG Linfeng   WANG Junjun   JIANG Lin*  

Department of Radiology, the Third Affiliated Hospital of Zunyi Medical University (the First People's Hospital of Zunyi), Zunyi 563000, China

Corresponding author: JIANG L, E-mail: jlinzmc@163.com

Conflicts of interest   None.

Received  2024-10-02
Accepted  2025-04-10
DOI: 10.12015/issn.1674-8034.2025.04.018
Cite this article as: GU X Y, ZHANG J R, SONG L F, et al. Research progress of Functional Connectivity in self-limited epilepsy with centrotemporal spikes[J]. Chin J Magn Reson Imaging, 2025, 16(4): 114-119, 138. DOI:10.12015/issn.1674-8034.2025.04.018.

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