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Neuroimaging advances in acupuncture for mild cognitive impairment
WANG Yixuan  LI Shuya  LIU Xuanli  YAO Yutong  LIN Jianwen  CAI Ming  LI Kuncheng  ZHAO Yawei  HAN Fang 

Cite this article as: WANG Y X, LI S Y, LIU X L, et al. Neuroimaging advances in acupuncture for mild cognitive impairment[J]. Chin J Magn Reson Imaging, 2025, 16(4): 120-125. DOI:10.12015/issn.1674-8034.2025.04.019.


[Abstract] Mild cognitive impairment (MCI) refers to the progressive decline of memory or other cognitive functions, which belongs to the early stage of Alzheimer's disease and is the key window of early diagnosis, prevention and treatment, and there is no drug radical cure. Acupuncture is widely used for its wide indications, quick response and simple operation, but its clinical treatment mechanism is still unclear. In recent years, with the rapid development of multimodal imaging technology and the continuous deepening of neuroimaging research on acupuncture treatment of MCI, the acupuncture treatment effect of MCI brain is accurately evaluated based on objective information such as structure, function and molecular imaging. It's convenient for early/ultra-early clinical treatment and intervention, provides objective evidence for the discussion of disease pathogenesis. This paper reviews the research progress of brain functional imaging technology in treating MCI patients with acupuncture, in order to provide new ideas for further revealing the mechanism of acupuncture on MCI diseases and a new perspective for clinical accurate diagnosis and treatment.
[Keywords] mild cognitive impairment；acupuncture；neuroimaging；functional magnetic resonance imaging；magnetic resonance imaging

WANG Yixuan1   LI Shuya1   LIU Xuanli1   YAO Yutong1   LIN Jianwen2   CAI Ming3   LI Kuncheng4   ZHAO Yawei1   HAN Fang5*  

1 Department of PET/CT Medical Center, Zhongshan Hospital Affiliated to Dalian University, Dalian 116001, China

2 Department of Psychiatry, Dalian University of Technology Affiliated Central Hospital, Dalian 116001, China

3 Department of Neurology, Zhongshan Hospital Affiliated to Dalian University, Dalian 116001, China

4 Department of Radiology and Nuclear Medicine, Xuanwu Hospital, Capital Medical University, Beijing 100053, China

5 Department of Imaging, Xinhua Hospital Affiliated to Dalian University, Dalian Key Laboratory of Functional and Molecular Imaging, Dalian 116001, China

Corresponding author: HAN F, E-mail: hanfang@dlu.edu.cn

Conflicts of interest   None.

Received  2024-11-12
Accepted  2025-04-10
DOI: 10.12015/issn.1674-8034.2025.04.019
Cite this article as: WANG Y X, LI S Y, LIU X L, et al. Neuroimaging advances in acupuncture for mild cognitive impairment[J]. Chin J Magn Reson Imaging, 2025, 16(4): 120-125. DOI:10.12015/issn.1674-8034.2025.04.019.

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