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Advances in functional magnetic resonance imaging in carotid artery stenosis and associated cognitive impairment
GAO Jiawen  ZHENG Ning  SHAO Shuo 

Cite this article as: GAO J W, ZHENG N, SHAO S. Advances in functional magnetic resonance imaging in carotid artery stenosis and associated cognitive impairment[J]. Chin J Magn Reson Imaging, 2025, 16(4): 161-167. DOI:10.12015/issn.1674-8034.2025.04.026.


[Abstract] Carotid artery stenosis (CAS) is a common vascular disease, which is not only closely related to the occurrence of ischaemic stroke, but also significantly associated with cognitive dysfunction, which seriously affects the quality of life of patients. Asymptomatic carotid stenosis (ACS) is carotid artery disease that has not yet resulted in a transient ischemic attack (TIA), ischemic stroke, or dementia. Even in asymptomatic patients with CAS, it can lead to significant cognitive dysfunction. In order to prevent further progression towards dementia, there is an urgent need to study the relationship between CAS and cognition. With the development of modern brain imaging technology, functional magnetic resonance imaging (fMRI) technology is able to sensitively detect abnormalities in brain tissue perfusion, structure and function, provided key imaging evidence to elucidate the mechanisms of CAS-related cognitive impairment. The purpose of this article is to review the latest research progress of fMRI technology in carotid artery stenosis and related cognitive impairment in recent years, in anticipation of providing new ideas for the assessment and diagnosis of CAS.
[Keywords] carotid stenosis；cognitive dysfunction；magnetic resonance imaging；brain function；functional connection

GAO Jiawen1   ZHENG Ning2, 3   SHAO Shuo2, 3*  

1 School of Medical Imaging, Shandong Second Medical University, Weifang 261053, China

2 Department of Radiology, Jining First People's Hospital, Jining 272000, China

3 Cognitive Disorders Specialized Disease Center of Jining First People's Hospital, Jining 272000, China

Corresponding author: SHAO S, E-mail: doubleshaoshuo@163.com

Conflicts of interest   None.

Received  2024-10-24
Accepted  2025-04-10
DOI: 10.12015/issn.1674-8034.2025.04.026
Cite this article as: GAO J W, ZHENG N, SHAO S. Advances in functional magnetic resonance imaging in carotid artery stenosis and associated cognitive impairment[J]. Chin J Magn Reson Imaging, 2025, 16(4): 161-167. DOI:10.12015/issn.1674-8034.2025.04.026.

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