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Research progress on the application of intravoxel incoherent motion in myocardial microcirculation
ZHAO Lei  XU Ning  WANG Cuiyan 

Cite this article as: ZHAO L, XU N, WANG C Y. Research progress on the application of intravoxel incoherent motion in myocardial microcirculation[J]. Chin J Magn Reson Imaging, 2025, 16(4): 174-179. DOI:10.12015/issn.1674-8034.2025.04.028.


[Abstract] Myocardial microcirculatory dysfunction serves as an independent risk factor for adverse cardiovascular events such as heart failure and cardiogenic sudden death. Early quantitative assessment of myocardial microcirculation has therefore become a research hotspot in cardiovascular imaging. Intravoxel incoherent movement (IVIM) magnetic resonance imaging, a technique capable of evaluating tissue microcirculatory function, provides a non-invasive, multi-parametric, and dynamically assessable novel perspective for early diagnosis of myocardial microcirculatory dysfunction. This paper systematically elaborates on the repeatability and stability of IVIM in myocardial microcirculation assessment, explores the quantitative characteristics of myocardial microcirculation under different pathological conditions using IVIM, and highlights the unresolved issues and emerging research directions in current IVIM-based myocardial microcirculation evaluations. This comprehensive review aims to enable subsequent researchers to grasp the latest developments in this field.
[Keywords] hypertensive cardiomyopathy；ischemic cardiomyopathy；hypertrophic cardiomyopathy；intravoxel incoherent movement；magnetic resonance imaging；myocardial microcirculation

ZHAO Lei1   XU Ning1   WANG Cuiyan2*  

1 Department of Imaging, Jinan Zhangqiu District People's Hospital, Jinan 250200, China

2 Department of Imaging, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan 250021, China

Corresponding author: WANG C Y, E-mail: wcyzhang@163.com

Conflicts of interest   None.

Received  2025-02-10
Accepted  2025-04-10
DOI: 10.12015/issn.1674-8034.2025.04.028
Cite this article as: ZHAO L, XU N, WANG C Y. Research progress on the application of intravoxel incoherent motion in myocardial microcirculation[J]. Chin J Magn Reson Imaging, 2025, 16(4): 174-179. DOI:10.12015/issn.1674-8034.2025.04.028.

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