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Research progress on bone marrow magnetic resonance imaging of aplastic anemia
CUI Xiaotian  GAO Mingjie  CHEN Tao  FU Qinghua  ZHANG Niulin  HAN Jihong  YOU Yilin  LI Zheyuan  WANG Jinhuan 

Cite this article as: CUI X T, GAO M J, CHEN T, et al. Research progress on bone marrow magnetic resonance imaging of aplastic anemia[J]. Chin J Magn Reson Imaging, 2025, 16(4): 214-220. DOI:10.12015/issn.1674-8034.2025.04.035.


[Abstract] Aplastic anemia (AA) is a bone marrow hematopoietic failure syndrome characterized by significant reduction in whole blood cells, low bone marrow proliferation capacity, and gradual replacement of hematopoietic tissue by adipose tissue. As a blood system disease that seriously threatens the life and health of patients, the current diagnosis of AA is still limited to exclusionary diagnosis. Finding clear and specific diagnostic criteria and biomarkers is still an important issue that needs to be addressed in the field of AA research. Accurate diagnosis and effective evaluation of the condition are of great significance for optimizing treatment plans and improving the prognosis of AA patients. MRI as a non-invasive and high-resolution imaging detection method, can effectively identify physiological and pathological changes in bone marrow based on different features provided by different sequences used, and analyze the internal structure of bone marrow. This detection method can effectively avoid the trauma and limitations of bone marrow puncture and other examinations. This article reviews the various applications of MRI in the field of bone marrow imaging research for AA, including the evaluation of AA lesions, determination of disease classification, dynamic monitoring of treatment efficacy, and differential diagnosis with other related hematological diseases. The aim is to provide reliable imaging theoretical basis for further in-depth research on the pathological basis of AA.
[Keywords] aplastic anemia；magnetic resonance imaging；bone marrow；diagnosis；imaging

CUI Xiaotian1   GAO Mingjie2   CHEN Tao1   FU Qinghua1   ZHANG Niulin1   HAN Jihong1   YOU Yilin1   LI Zheyuan1   WANG Jinhuan2*  

1 Graduate School of Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China

2 Department of Hematology, the First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China

Corresponding author: WANG J H, E-mail: wjh_0304@163.com

Conflicts of interest   None.

Received  2024-12-27
Accepted  2025-04-10
DOI: 10.12015/issn.1674-8034.2025.04.035
Cite this article as: CUI X T, GAO M J, CHEN T, et al. Research progress on bone marrow magnetic resonance imaging of aplastic anemia[J]. Chin J Magn Reson Imaging, 2025, 16(4): 214-220. DOI:10.12015/issn.1674-8034.2025.04.035.

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