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Research progress of PCASL imaging technology artifact and its clinic
LI Zhongxin  HE Yexin 

Cite this article as: LI Z X, HE Y X. Research progress of PCASL imaging technology artifact and its clinic[J]. Chin J Magn Reson Imaging, 2025, 16(4): 228-234. DOI:10.12015/issn.1674-8034.2025.04.037.


[Abstract] Arterial spin labeling (ASL) is a non-invasive magnetic resonance perfusion imaging technique that uses magnetically labeled water in flowing blood as an endogenous tracer to assess cerebral blood flow (CBF). At present, it has demonstrated unique clinical value in cerebrovascular diseases, brain tumors, epilepsy and neurodegenerative diseases. With the continuous development of technology, it can be divided into four categories according to different pulse methods, and the most commonly used technology in clinical practice is pseudocontinuous ASL (PCASL). Although PCASL technology has shown great potential in clinical applications, it still faces the problem of artifact generation during imaging. These artifacts may occur at all stages of imaging, and can be divided into three main categories: during labeling, during arterial transmission, and during readout, and the causes and manifestations of artifacts are complex. Therefore, it is of great significance to further improve the accuracy and reliability of PCASL technology in clinical applications. This article reviews the performance characteristics, causes, remedial measures, and potential clinical value of PCASL technical artifacts, in order to explore its clinical value and improve the practicability and reliability of PCASL in the field of neuroimaging.
[Keywords] magnetic resonance imaging；arterial spin labeling；artifacts；pseudocontinuous arterial spin labeling；arterial transit time；post label delay

LI Zhongxin1   HE Yexin2*  

1 Department of Medical Imaging, Shanxi Medical University, Taiyuan 030001, China

2 Department of Radiology, Shanxi Provincial People's Hospital, Fifth Clinical College of Shanxi Medical University, Taiyuan 030012, China

Corresponding author: HE Y X, E-mail: heyexinty2000@sina.com

Conflicts of interest   None.

Received  2024-10-09
Accepted  2025-04-10
DOI: 10.12015/issn.1674-8034.2025.04.037
Cite this article as: LI Z X, HE Y X. Research progress of PCASL imaging technology artifact and its clinic[J]. Chin J Magn Reson Imaging, 2025, 16(4): 228-234. DOI:10.12015/issn.1674-8034.2025.04.037.

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