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• Clinical Article •
Predictive efficiency of magnetic resonance vessel wall imaging on vertebrobasilar dolichoectasia with posterior circulation infarction
SUN Ruixue  CHANG Ruiting  YU Tianshu  WANG Yanming  KANG Zhilei 

Cite this article as: SUN R X, CHANG R T, YU T S, et al. Predictive efficiency of magnetic resonance vessel wall imaging on vertebrobasilar dolichoectasia with posterior circulation infarction[J]. Chin J Magn Reson Imaging, 2025, 16(7): 15-21. DOI:10.12015/issn.1674-8034.2025.07.003.


[Abstract] Objective To explore the predictive efficiency of 3.0 T high-resolution magnetic resonance vessel wall imaging (HRMR-VWI) on vertebrobasilar dolichoectasia (VBD) with posterior circulation infarction.Materials and Methods The clinical data of 200 patients with VBD in the hospital were retrospectively analyzed from May 2021 to June 2024. All patients received HRMR-VWI examination, and were followed up until March 2025. During follow-up, 4 cases were lost to follow-up for personal reasons, with the shedding rate of 2.00%. The patients were divided into study group (with posterior circulation infarction, 142 cases) and control group (without posterior circulation infarction, 54 cases) according to whether they were complicated with posterior circulation infarction. The predictive value of HRMR-VWI indicators on VBD with posterior circulation infarction was analyzed. According to the degree of vascular stenosis, the patients in study group were classified into mild stenosis (25% ≤ measured vascular stenosis rate < 50%), moderate stenosis (50% ≤ measured vascular stenosis rate < 70%) and severe stenosis (measured vascular stenosis rate ≥ 70%). The relationship between HRMR-VWI indicators and vascular stenosis degree in patients with posterior circulation infarction was analyzed.Results The lumen area at the narrowest level in study group was smaller than that in control group while the vascular wall area and plaque area were larger than those in control group, and the plaque load and remodeling index were higher, with statistical differences (P < 0.05). Receiver operating characteristic (ROC) curve showed that the area under the curve (AUC) of combined detection of HRMR-VWI indicators in predicting VBD with posterior circulation infarction was greater than that of single detection of each indicator, with a statistical significance (P < 0.05). The levels of triglyceride, total cholesterol, low density lipoprotein, apolipoprotein A1 and fibrinogen in study group were higher while and the level of high density lipoprotein was lower than that in control group, and the proportions of patients with lumen area < 3.08 mm2, vascular wall area ≥ 10.65 mm2, plaque area ≥ 3.14 mm2, plaque load ≥ 0.74 and remodeling index ≥ 1.01 were higher, with statistical differences (P < 0.05). The increases of total cholesterol, apolipoprotein A1 and fibrinogen, reduction of lumen area at the narrowest level, reduction of vascular wall area, enlargement of plaque area and increases of plaque load and remodeling index were the risk factors of VBD with posterior circulation infarction (P < 0.05). The proportions of BA and VA unstable plaques in study group were higher than those in control group, with statistical differences (P < 0.05). In VBD patients, the blood vessel area and lumen area at the narrowest level were negatively correlated with the degree of vascular stenosis while the plaque area, plaque load and remodeling index were positively correlated with the degree of vascular stenosis (P < 0.05).Conclusions 3.0 T HRMR-VWI has predictive value on VBD patients with posterior circulation infarction, and the changes of HRMR-VWI indicators are related to posterior circulation infarction in patients.
[Keywords] high-resolution magnetic resonance imaging；vessel wall imaging guidance；vertebrobasilar dolichoectasia；posterior circulation infarction；predictive value

SUN Ruixue1   CHANG Ruiting1   YU Tianshu2   WANG Yanming1   KANG Zhilei1*  

1 Imaging Center, Hengshui People's Hospital, Hengshui 053000, China

2 Department of Nuclear Medicine, Hengshui People's Hospital, Hengshui 053000, China

Corresponding author: KANG Z L, E-mail: 85080695@qq.com

Conflicts of interest   None.

Received  2025-02-25
Accepted  2025-07-04
DOI: 10.12015/issn.1674-8034.2025.07.003
Cite this article as: SUN R X, CHANG R T, YU T S, et al. Predictive efficiency of magnetic resonance vessel wall imaging on vertebrobasilar dolichoectasia with posterior circulation infarction[J]. Chin J Magn Reson Imaging, 2025, 16(7): 15-21. DOI:10.12015/issn.1674-8034.2025.07.003.

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