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Research progress of multimodal MRI in mild traumatic brain injury
LÜ Zihan  CUI Jie  ZHONG Yeming  CHE Zigang 

Cite this article as: LÜ Z H, CUI J, ZHONG Y M, et al. Research progress of multimodal MRI in mild traumatic brain injury[J]. Chin J Magn Reson Imaging, 2025, 16(7): 129-134. DOI:10.12015/issn.1674-8034.2025.07.021.


[Abstract] Mild traumatic brain injury (mTBI) accounts for over 80% of all traumatic brain injury (TBI) cases and is one of the common neurological disorders. However, the current understanding of the diagnosis of mTBI and the underlying neurophysiological mechanisms of post-traumatic cognitive changes remains incomplete. This lack of clarity hinders the early diagnosis, treatment decision-making, and prognosis evaluation for mTBI. In recent years, an increasing number of multimodal magnetic resonance imaging (MRI) techniques have been applied to the diagnosis of mTBI. These include functional magnetic resonance imaging (fMRI), arterial spin labeling (ASL) perfusion imaging, susceptibility-weighted imaging (SWI), and diffusion tensor imaging (DTI). These techniques have enhanced our understanding of the neuropathological mechanisms of mTBI from different perspectives. This article reviews the application progress of the above-mentioned multimodal MRI techniques in mTBI and evaluates their advantages and disadvantages, providing new ideas for future research.
[Keywords] mild traumatic brain injury；functional magnetic resonance imaging；arterial spin labeling perfusion imaging；susceptibility-weighted imaging；diffusion tensor imaging

LÜ Zihan   CUI Jie   ZHONG Yeming   CHE Zigang*  

Department of Medical Imaging, Nanjing Tongren Hospital, School of Medicine, Southeast University, Nanjing 211102, China

Corresponding author: CHE Z G, E-mail: chezg@njtrh.org

Conflicts of interest   None.

Received  2024-12-27
Accepted  2025-07-05
DOI: 10.12015/issn.1674-8034.2025.07.021
Cite this article as: LÜ Z H, CUI J, ZHONG Y M, et al. Research progress of multimodal MRI in mild traumatic brain injury[J]. Chin J Magn Reson Imaging, 2025, 16(7): 129-134. DOI:10.12015/issn.1674-8034.2025.07.021.

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