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• Technical Article •
Non-contrast magnetic resonance coronary angiography based on fast 3D and R-wave correction techniques: A comparative study with computed tomography angiography
CHEN Yufeng  CHEN Zhentao  HU Chunfeng 

DOI:10.12015/issn.1674-8034.2025.08.019.


[Abstract] Objective To investigate the image quality, morphological evaluation, and diagnostic accuracy of 3.0 T non-contrast magnetic resonance coronary angiography (MRCA) using Fast 3D and R-wave correction techniques in patients with coronary artery disease (CAD) for detecting ≥ 50% coronary stenosis.Materials and Methods Forty-six CAD patients were prospectively enrolled and underwent 3.0 T MRCA within 48 to 72 hours after coronary computed tomography angiography (CCTA). The MRCA protocol incorporated R-wave correction (trigger interval ± 15%) and Fast 3D. Two radiologists independently assessed MRCA image quality (5-point scale) and coronary stenosis. Generalized Estimating Equations (GEE) analyzed image quality across eight coronary segments. Bland-Altman analysis evaluated vessel length consistency between MRCA and CCTA, while receiver operating characteristic curves assessed diagnostic performance for ≥ 50% stenosis.Results The MRCA examination success rate was 89.13% (41/46), with an excellent image rate of 65.85%. Image quality scores for proximal right coronary artery (RCA) and left anterior descending coronary artery (LAD) segments were superior to distal segments (P < 0.05). Higher heart rate (≥ 70 bpm) and body mass index (BMI) (≥ 25 kg/m2) significantly reduced image quality (P < 0.05). MRCA and CCTA showed good consistency in vessel length (95% limits of agreement: -5.94 to -0.68; outlier rate < 5%), except for left circumflex branch (LCX) (9.76% outlier rate). For ≥ 50% stenosis, MRCA demonstrated a sensitivity of 81.08%, specificity of 95.29%, and area under the curve of 0.889 (95% confidence interval: 0.819 to 0.938).Conclusions 3.0 T MRCA with Fast 3D and R-wave correction techniques demonstrated high examination success rate and excellent image quality in CAD patients. Morphologically, the display of vessel length is in good agreement with CCTA in RCA and LAD. It can serve as an effective non-invasive screening tool for coronary artery assessment, particularly suitable for patients with contrast agent contraindications or requiring radiation avoidance.
[Keywords] coronary artery disease；magnetic resonance imaging；magnetic resonance coronary angiography；Fast 3D technique；R-wave correction technique；image quality；diagnostic performance​

CHEN Yufeng1, 2   CHEN Zhentao3   HU Chunfeng1*  

1 Department of Radiology, the Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, China

2 Department of Radiology, Xuzhou Renci Hospital, Xuzhou 221004, China

3 Department of MR Clinical Research, Canon Medical Systems (China), Beijing 100027, China

Corresponding author: HU C F, E-mail: hcfxz@163.com

Conflicts of interest   None.

Received  2025-05-08
Accepted  2025-08-08
DOI: 10.12015/issn.1674-8034.2025.08.019
DOI:10.12015/issn.1674-8034.2025.08.019.

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