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• Clinical Article •
Analysis of MR imaging evolution and related factors of recent small subcortical infarcts with cerebral small vessel disease
HE Xueping  YE Yufeng  LI Yanhua  ZHUANG Gaoming  LIU Dexiang  WANG Li 

Cite this article as: HE X P, YE Y F, LI Y H, et al. Analysis of MR imaging evolution and related factors of recent small subcortical infarcts with cerebral small vessel disease[J]. Chin J Magn Reson Imaging, 2025, 16(9): 22-27. DOI:10.12015/issn.1674-8034.2025.09.004.


[Abstract] Objective To explore related factors affecting MRI evolution of recent small subcortical infarct (RSSI).Materials and Methods A total of 105 patients with RSSI were admitted between August 2019 and September 2024. There were 78 males and 27 females, with mean age (62.77 ± 13.28) years. Clinical information of patients, images data of head MRI were collected. All patients were divided into cavitation group and no cavitation group [white matter hyperintensities (WMH) and disappearance] to analyze related factors affecting evolution with multivariate logistic regression analysis.Results Sixty-three cases (60.00%) developed to cavities, 34 cases (32.38%) evolved into WMH, and 8 cases (7.62%) disappeared. There were significant differences in gender, initial diffusion-weighted imaging (DWI) infarct diameter and number of old lacunes lesion between the two groups (P < 0.05). In logistic regression analysis, initial DWI infarct diameter (OR = 1.394, P < 0.001) and number of old lacunes (OR = 1.455, P = 0.028) was an independent predictor of cavity formation.Conclusions About 60% of RSSI develop to cavitation. All infarct lesions were reduced during follow-up. The RSSI showing larger diameter of infarct lesions and more number of old lacunar infarction have a greater possibility of cavitation.
[Keywords] small subcortical infarct；cerebral small vessel disease；magnetic resonance imaging；imaging evolution；infarct diameter；old lacunes

HE Xueping1   YE Yufeng1, 2   LI Yanhua1   ZHUANG Gaoming1   LIU Dexiang1*   WANG Li1, 2  

1 Department of Radiology, the Affiliated Panyu Central Hospital of Guangzhou Medical University, Guangzhou 511400, China

2 Medical Imaging Institute of Panyu District, Guangzhou 511400, China

Corresponding author: LIU D X, E-mail: xiangmail3@21cn.com

Conflicts of interest   None.

Received  2025-05-07
Accepted  2025-09-03
DOI: 10.12015/issn.1674-8034.2025.09.004
Cite this article as: HE X P, YE Y F, LI Y H, et al. Analysis of MR imaging evolution and related factors of recent small subcortical infarcts with cerebral small vessel disease[J]. Chin J Magn Reson Imaging, 2025, 16(9): 22-27. DOI:10.12015/issn.1674-8034.2025.09.004.

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