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• Clinical Article •
Application value of susceptibility-weighted imaging for neonatal craniocerebral injury
ZHANG Siqi  LI Zhiqiang  WANG Ruirui  WEI Lijuan  WANG Biao  BAI Juan  ZHANG Yong  GUAN Hanzhou  XU Shuming 

Cite this article as: ZHANG S Q, LI Z Q, WANG R R, et al. Application value of susceptibility-weighted imaging for neonatal craniocerebral injury[J]. Chin J Magn Reson Imaging, 2025, 16(9): 34-39. DOI:10.12015/issn.1674-8034.2025.09.006.


[Abstract] Objective To evaluate the value of susceptibility weighted imaging (SWI) in the diagnosis and differential diagnosis of neonatal craniocerebral injury.Materials and Methods A retrospective collection of 900 neonates suspected of intracranial hemorrhage (ICH) after cranial ultrasound screening in Shanxi Children's Hospital was completed with conventional MRI and SWI. The chi-square test was used to compare the detection rates of conventional MRI and SWI for different hemorrhage sites. The chi-square test was used to evaluate the differences in different sites of ICH in preterm and term infants.Results (1) SWI has a higher detection rate of neonatal ICH than conventional MRI (24.0% vs. 19.8%, P < 0.05); (2) For hemorrhage in the lateral ventricles, cerebral cortex, cerebellar hemispheres, and subdural/epidural hemorrhages, SWI detects a greater number and extent of lesions than conventional MRI (P < 0.05); (3) The detection rate of hemorrhage lesions in germinal matrix and lateral compartment was higher in preterm infants than term infants, and the detection rate of hemorrhage lesions in subarachnoid space was lower than in term infants (P < 0.05).Conclusions SWI is somewhat superior to conventional MRI in detecting neonatal ICH and identifying punctate white matter lesion and microhemorrhagic lesions. Therefore, it is recommended that conventional MRI combined with SWI sequences should be used for comprehensive diagnosis in order to improve the efficacy of detecting ICH lesions and provide an imaging basis for clinical diagnosis and treatment.
[Keywords] neonate；intracranial hemorrhage；punctate white matter lesion；susceptibility-weighted imaging；magnetic resonance imaging

ZHANG Siqi1   LI Zhiqiang2   WANG Ruirui3   WEI Lijuan4   WANG Biao1   BAI Juan5   ZHANG Yong3   GUAN Hanzhou3   XU Shuming1*  

1 Department of CT, Shanxi Children's Hospital (Shanxi Maternal and Child Health Hospital), Taiyuan 030013, China

2 Department of imaging, Taiyuan Maternal and Child Health Hospital, Taiyuan 030012, China

3 Department of Intensive Care, Shanxi Children's Hospital (Shanxi Maternal and Child Health Hospital), Taiyuan 030013, China

4 Department of CT, Shanxi Coal Central Hospital, Taiyuan 030006, China

5 Department of MRI, Shanxi Cardiovascular Disease Hospital, Taiyuan 030027, China

Corresponding author: XU S M, E-mail: mrixsm2006@163.com

Conflicts of interest   None.

Received  2024-08-18
Accepted  2025-09-03
DOI: 10.12015/issn.1674-8034.2025.09.006
Cite this article as: ZHANG S Q, LI Z Q, WANG R R, et al. Application value of susceptibility-weighted imaging for neonatal craniocerebral injury[J]. Chin J Magn Reson Imaging, 2025, 16(9): 34-39. DOI:10.12015/issn.1674-8034.2025.09.006.

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