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• Technical Article •
A preliminary study on improving liver dynamic contrast-enhanced MRI quality in patients with poor breath-holding using the optimized compressed sensing golden-angle radial sparse parallel sampling sequence
PAN Jiangyang  WANG Qi  SHI Gaofeng  MAO Ziyi  LI Yang  JIANG Yueluan  LIU Hui 

Cite this article as: PAN J Y, WANG Q, SHI G F, et al. A preliminary study on improving liver dynamic contrast-enhanced MRI quality in patients with poor breath-holding using the optimized compressed sensing golden-angle radial sparse parallel sampling sequence[J]. Chin J Magn Reson Imaging, 2025, 16(9): 162-168. DOI:10.12015/issn.1674-8034.2025.09.024.


[Abstract] Objective To explore the optimized scanning scheme for compressed sensing golden-angle radial sparse parallel sequence (CS-GRASP) and evaluate the application value of the optimized sequence in liver dynamic contrast-enhanced MRI (DCE-MRI) for patients with poor breath-holding.Materials and Methods This retrospective analysis was conducted on 46 patients with poor breath-holding capability who underwent dynamic contrast enhanced-magnetic resonance imaging of the liver at our hospital from March 2021 to October 2023, including 21 patients in the unoptimized CS-GRASP group and 25 patients in the optimized group. Signal intensity (SI) of the liver and erector spinae, standard deviation (SD), and the mean standard deviation of image background noise (SD noise) were measured at the levels of the main hepatic portal vein and its left and right branches during non-contrast, early arterial, and late arterial phases. The signal-to-noise ratio (SNR), contrast-noise ratio (CNR), and coefficient of variation (CV) of SI for liver CS-GRASP images of both groups were calculated. Subjective scoring was conducted for image noise, the severity of streak artifacts, image quality, and clarity of liver structures in the left and right liver lobes.Results During plain scanning, arterial early phase, and arterial late phase, the SNR and CNR of images of the left and right lobes of the liver in the CS-GRASP optimized group was higher than those in the unoptimized group, and the CV values were lower than that of the unoptimized group; the difference in CNR of the arterial early phase of the right lobe of the liver was not statistically significant between the two groups (P > 0.05), while the difference of the rest of the parameters were statistically significant (P < 0.05). In the CS-GRASP optimized group, scores for image noise and streak artifacts of the left and right liver lobes, scores for image clarity, and overall image quality were higher than those in the non-optimized group, with statistically significant differences (P < 0.05).Conclusions The optimized CS-GRASP sequence can improve image quality and reduce streak artifacts, making it a better alternative for patients with poor breath-holding during liver contrast-enhanced MRI.
[Keywords] liver；poor breath-holding；magnetic resonance imaging；golden-angle radial sparse parallel；imaging quality

PAN Jiangyang1   WANG Qi1   SHI Gaofeng1   MAO Ziyi1   LI Yang1   JIANG Yueluan2   LIU Hui1*  

1 Department of CT/MRI, No. 4 Hospital of Hebei Medical University, Shijiazhuang 050000, China

2 Beijing Branch, Siemens Medical Systems Ltd., Beijing 100102, China

Corresponding author: LIU H, E-mail: 48801893@hebmu.edu.cn

Conflicts of interest   None.

Received  2025-03-21
Accepted  2025-09-10
DOI: 10.12015/issn.1674-8034.2025.09.024
Cite this article as: PAN J Y, WANG Q, SHI G F, et al. A preliminary study on improving liver dynamic contrast-enhanced MRI quality in patients with poor breath-holding using the optimized compressed sensing golden-angle radial sparse parallel sampling sequence[J]. Chin J Magn Reson Imaging, 2025, 16(9): 162-168. DOI:10.12015/issn.1674-8034.2025.09.024.

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