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Research progress on resting-state functional magnetic resonance imaging in post-stroke depression
QIAN Jinhua  CHI Qinjie  DING Wenbin  WANG Tianle  ZHU Li 

Cite this article as: QIAN J H, CHI Q J, DING W B, et al. Research progress on resting-state functional magnetic resonance imaging in post-stroke depression[J]. Chin J Magn Reson Imaging, 2025, 16(9): 181-187. DOI:10.12015/issn.1674-8034.2025.09.027.


[Abstract] Post-stroke depression (PSD) is a common neuropsychiatric complication following stroke, significantly affecting patients' functional recovery, mental and physical health, and long-term prognosis. In recent years, resting-state functional magnetic resonance imaging (rs-fMRI), a noninvasive and repeatable brain imaging technique, has been increasingly utilized to reveal spontaneous neural activity and functional connectivity patterns. This approach provides important neuroimaging evidence for understanding the underlying neural mechanisms of PSD and holds potential for early diagnosis and prognosis prediction. This review systematically summarizes the major findings, emerging analytical methods, and clinical implications of rs-fMRI in PSD research. It also discusses the limitations of existing studies and proposes future research directions, aiming to provide new insights in the mechanistic study and clinical management of PSD.
[Keywords] stroke；post-stroke depression；resting-state；functional magnetic resonance imaging；magnetic resonance imaging

QIAN Jinhua1, 2   CHI Qinjie1   DING Wenbin1   WANG Tianle2   ZHU Li2*  

1 Department of Interventional Radiology, the Second Affiliated Hospital of Nantong University, Nantong 226600, China

2 Department of Radiology, the Second Affiliated Hospital of Nantong University, Nantong 226600, China

Corresponding author: ZHU L, E-mail: 9364923@qq.com

Conflicts of interest   None.

Received  2025-06-09
Accepted  2025-09-03
DOI: 10.12015/issn.1674-8034.2025.09.027
Cite this article as: QIAN J H, CHI Q J, DING W B, et al. Research progress on resting-state functional magnetic resonance imaging in post-stroke depression[J]. Chin J Magn Reson Imaging, 2025, 16(9): 181-187. DOI:10.12015/issn.1674-8034.2025.09.027.

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