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Advances in the application of magnetic resonance imaging and repetitive transcranial magnetic stimulation for generalized anxiety disorder
ZHANG Yuhang  LIU Bingqian  WANG Meiyun 

Cite this article as: ZHANG Y H, LIU B Q, WANG M Y. Advances in the application of magnetic resonance imaging and repetitive transcranial magnetic stimulation for generalized anxiety disorder[J]. Chin J Magn Reson Imaging, 2025, 16(10): 114-118, 136. DOI:10.12015/issn.1674-8034.2025.10.018.


[Abstract] Generalized anxiety disorder (GAD), a psychiatric condition with a relatively high global prevalence, is one of the most common forms of anxiety disorders. Repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, has demonstrated potential in the treatment of GAD. This review summarizes research on aberrant functional connectivity in the brains of GAD patients using MRI, as well as the role of MRI in guiding rTMS therapy, elucidating its neural mechanisms, and evaluating treatment efficacy. Current limitations are discussed, and future research directions are proposed, highlighting the integration of MRI with rTMS to offer novel insights for personalized treatment of GAD.
[Keywords] generalized anxiety disorder；magnetic resonance imaging；repetitive transcranial magnetic stimulation；functional connectivity；medical imaging

ZHANG Yuhang1, 2   LIU Bingqian1, 2   WANG Meiyun2, 3*  

1 Department of Medical Imaging, Henan University People's Hospital, Zhengzhou 450003, China

2 Department of Medical Imaging, Henan Provincial People's Hospital, Zhengzhou 450003, China

3 Biomedical Research Institute, Henan Academy of Sciences, Zhengzhou 450046, China

Corresponding author: WANG M Y, E-mail: mywang@zzu.edu.cn

Conflicts of interest   None.

Received  2025-07-04
Accepted  2025-10-10
DOI: 10.12015/issn.1674-8034.2025.10.018
Cite this article as: ZHANG Y H, LIU B Q, WANG M Y. Advances in the application of magnetic resonance imaging and repetitive transcranial magnetic stimulation for generalized anxiety disorder[J]. Chin J Magn Reson Imaging, 2025, 16(10): 114-118, 136. DOI:10.12015/issn.1674-8034.2025.10.018.

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