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Research progress of imaging evaluation of hemorrhagic transformation after thrombolysis in acute ischemic stroke
JI Xinggui  ZHANG Ruijie  LIU Zhenhe  ZHANG Huan  LIU Tong  SU Tong  XU Wanbo 

Cite this article as: JI X G, ZHANG R J, LIU Z H, et al. Research progress of imaging evaluation of hemorrhagic transformation after thrombolysis in acute ischemic stroke[J]. Chin J Magn Reson Imaging, 2025, 16(10): 130-136. DOI:10.12015/issn.1674-8034.2025.10.021.


[Abstract] The incidence of acute ischemic stroke is increasing day by day. Intravenous thrombolysis is one of the effective methods to treat AIS patients with great vascular occlusion within the time window, but hemorrhagic after thrombolysis is one of its main complications. It is necessary to accurately evaluate whether acute ischemic stroke patients can benefit from thrombolysis. At present, there are many clinical scoring tables, laboratory and imaging indicators to predict the hemorrhagic transformation after thrombolysis. The review points out the limitations of previous research and points out the direction of future research. In this paper, the research progress of hemorrhagic transformation classification, imaging characteristics and artificial intelligence is reviewed, aiming at providing reference for clinical diagnosis and treatment.
[Keywords] acute ischemic stroke；hemorrhagic transformation；computed tomography；magnetic resonance imaging；artificial intelligence；prediction

JI Xinggui1   ZHANG Ruijie2   LIU Zhenhe2   ZHANG Huan2   LIU Tong2   SU Tong2   XU Wanbo2*  

1 Shandong Second Medical Univeristy School of Medical Imaging, Weifang 261053, China

2 Department of Radiology, Qilu Hospital of Shandong University Dezhou Hospital, Dezhou 253000, China

Corresponding author: XU W B, E-mail: 18005342388@163.com

Conflicts of interest   None.

Received  2025-07-23
Accepted  2025-10-08
DOI: 10.12015/issn.1674-8034.2025.10.021
Cite this article as: JI X G, ZHANG R J, LIU Z H, et al. Research progress of imaging evaluation of hemorrhagic transformation after thrombolysis in acute ischemic stroke[J]. Chin J Magn Reson Imaging, 2025, 16(10): 130-136. DOI:10.12015/issn.1674-8034.2025.10.021.

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