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Advances in the application of CMR based radiomics in cardiac diseases
ZHOU Lei  WU Yousen  ZHANG Qian  ZHOU Boqi 

Cite this article as: ZHOU L, WU Y S, ZHANG Q, et al. Advances in the application of CMR based radiomics in cardiac diseases[J]. Chin J Magn Reson Imaging, 2025, 16(10): 164-170. DOI:10.12015/issn.1674-8034.2025.10.026.


[Abstract] Cardiovascular diseases, ranking among the leading causes of death globally, exhibit heterogeneous spectrum of clinical phenotypes. They are often insidious in onset, frequently progressing to an irreversible stage by the time of diagnosis, therapeutic effectiveness and impairing patients' quality of life. Early and precise diagnosis is therefore a critical strategy for improving prognosis. Traditional cardiac magnetic resonance (CMR) analysis methods have limitations in utilizing image information, The emergence of CMR radiomics has introduced a breakthrough in the diagnosis and treatment of cardiac diseases. This advanced technique enables the extraction of high-dimensional features from medical images, demonstrating significant advantages in the phenotyping, severity assessment, and progression evaluation of various cardiac conditions. However, current studies are mostly based on single-center, small-sample cohorts and lack external validation; imaging scan parameters and post-processing procedures have not been standardized, the reproducibility and biological interpretability of radiomics features remain insufficient, and models are still at the offline validation stage, lacking evidence for real-time decision support integrated with clinical workflows, which severely limits the speed and scope of translating CMR radiomics into clinical practice. In view of this,this review aims to review the key technical advances and clinical translations of CMR radiomics in the diagnosis and prognosis prediction of various cardiac conditions. It will also analyze current challenges and future directions, with the goal of providing an evidence-based foundation for clinical practice. Ultimately, this review seeks to foster early disease identification and improved prognosis management, thereby enhancing patient quality of life and clinical outcomes.
[Keywords] cardiac diseases；radiomics；cardiac magnetic resonance；magnetic resonance imaging；diagnosis；prognostic evaluation

ZHOU Lei   WU Yousen*   ZHANG Qian   ZHOU Boqi  

Image Center, Affiliated Hospital of Qinghai University, Xining 810001, China

Corresponding author: WU Y S, E-mail: wuyousen@163.com

Conflicts of interest   None.

Received  2025-08-04
Accepted  2025-10-08
DOI: 10.12015/issn.1674-8034.2025.10.026
Cite this article as: ZHOU L, WU Y S, ZHANG Q, et al. Advances in the application of CMR based radiomics in cardiac diseases[J]. Chin J Magn Reson Imaging, 2025, 16(10): 164-170. DOI:10.12015/issn.1674-8034.2025.10.026.

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