Research progress in multiparametric MRI for evaluating extraprostatic extension of prostate cancer

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ZHANG Biao SUN Meiyu

Cite this article as: ZHANG B, SUN M Y. Research progress in multiparametric MRI for evaluating extraprostatic extension of prostate cancer[J]. Chin J Magn Reson Imaging, 2025, 16(10): 208-214. DOI:10.12015/issn.1674-8034.2025.10.033.

Abstract

[Abstract] Extraprostatic extension (EPE) of prostate cancer (PCa) is closely related to poor prognostic factors such as positive surgical margin, biochemical recurrence and distant metastasis after PCa surgery, which seriously affects the survival rate of PCa patients. Preoperative MRI evaluation of EPE is helpful to develop individualized surgical plans and improve the quality of life of patients. The multiparametric MRI (mpMRI) techniques recommended by prostate imaging reporting and data system (PI-RADS) include T2WI, dynamic contrast-enhanced (DCE), and diffusion-weighted imaging (DWI). At present, the review of mpMRI in the prediction of EPE mostly focuses on the discussion of imaging signs, and rarely elaborates from the perspective of technological application. This article reviews the technical applicationand research progress of T2WI, DCE and DWI techniques in the evaluation of EPE, systematically introduces the principles and imaging characteristics of these techniques, and discusses their diagnostic value, limitations and development directions in the evaluation of EPE, aiming to provide technical reference for the accurate evaluation of EPE in PCa, optimize MRI scanning scheme and imaging analysis methods for preoperative EPE prediction , and promote the individualized diagnosis and treatment of PCa.

[Keywords] prostate cancer；extraprostatic extension；magnetic resonance imaging；diffusion-weighted imaging；dynamic contrast-enhanced

Contributor Information

ZHANG Biao SUN Meiyu^*

Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

Corresponding author: SUN M Y, E-mail: sunmy828@126.com

Conflicts of interest None.

Publication Information

Received 2025-05-30

Accepted 2025-10-10

DOI: 10.12015/issn.1674-8034.2025.10.033

Text

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