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Research progress of cardiac magnetic resonance feature tracking technology in the assessment of multi-chamber strain in hypertrophic cardiomyopathy
HUANG Yifan  WANG Xiaoyan  FAN Hongwei  SUN Linbing  ZHANG Aoyang  SONG Peiji 

Cite this article as: HUANG Y F, WANG X Y, FAN H W, et al. Research progress of cardiac magnetic resonance feature tracking technology in the assessment of multi-chamber strain in hypertrophic cardiomyopathy[J]. Chin J Magn Reson Imaging, 2026, 17(3): 187-193, 200. DOI:10.12015/issn.1674-8034.2026.03.027.


[Abstract] Hypertrophic cardiomyopathy (HCM) is a common hereditary cardiomyopathy in clinical practice and one of the important causes of sudden cardiac death (SCD) in adolescents and young adults. Therefore, early identification and accurate assessment are crucial. Cardiac magnetic resonance feature tracking technology (CMR-FT) can non-invasively and quantitatively assess global myocardial strain based on conventional cine sequences, and has become a research hotspot in HCM cardiac function assessment in recent years. This review systematically expounds the basic principles, derivative parameters and advantages of CMR-FT, focusing on its core applications in the assessment of left and right ventricular, and left and right atrial strain in HCM, including early identification, obstruction phenotype differentiation, differential diagnosis, and risk stratification, etc. It clarifies the limitations such as insufficient technical standardization and analyzing the future development direction of multi-parameter model construction and artificial intelligence integration, so as to provide reference for the accurate clinical assessment of cardiac function and optimization of diagnosis and treatment strategies in HCM patients, and promote the integration of this technology into the whole-course management of HCM.
[Keywords] hypertrophic cardio myopathy；sudden cardiac death；magnetic resonance imaging；cardiac magnetic resonance；feature tracking；myocardial strain；cardiac function assessment

HUANG Yifan1   WANG Xiaoyan2   FAN Hongwei2   SUN Linbing1   ZHANG Aoyang3   SONG Peiji2*  

1 School of Medical Imaging, Shandong Second Medical University, Weifang 261053, China

2 Department of Radiology, Central Hospital Affiliated to Shandong First Medical University, Jinan 250013, China

3 Graduate Department, Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan 250117, China

Corresponding author: SONG P J, E-mail: 1597292215@qq.com

Conflicts of interest   None.

Received  2025-12-23
Accepted  2026-03-03
DOI: 10.12015/issn.1674-8034.2026.03.027
Cite this article as: HUANG Y F, WANG X Y, FAN H W, et al. Research progress of cardiac magnetic resonance feature tracking technology in the assessment of multi-chamber strain in hypertrophic cardiomyopathy[J]. Chin J Magn Reson Imaging, 2026, 17(3): 187-193, 200. DOI:10.12015/issn.1674-8034.2026.03.027.

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