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Research progress on brain effect characteristics of acupuncture at different points in treating Alzheimer's disease based on rs-fMRI
ZHAO Siyi  ZHU Jinyi  ZHANG Miao 

DOI:10.12015/issn.1674-8034.2026.05.019.


[Abstract] Alzheimer's Disease (AD) is a progressive neurodegenerative disease with a complex mechanism. After onset, it causes a series of clinical manifestations of cognitive and behavioral disorders in patients. Currently, there is no cure for this disease. With the widespread application of acupuncture treatment and the development of resting-state functional magnetic resonance imaging (rs-fMRI), the research on the pathogenesis and intervention measures of AD has received increasing attention, and it also provides reliable technical support for the exploration of specific acupuncture points. This article reviews the abnormal brain functional areas and networks related to AD and the specific acupuncture points of acupuncture treatment for AD based on rs-fMRI, with the aim of providing references for optimizing acupuncture treatment plans in clinical practice and improving therapeutic efficacy. This article points out the limitations of the current research and indicates the direction for future studies.
[Keywords] Alzheimer's disease；magnetic resonance imaging；functional magnetic resonance imaging；resting-state functional magnetic resonance imaging；acupuncture；brain functional network；specific acupuncture points

ZHAO Siyi1   ZHU Jinyi1   ZHANG Miao2*  

1 Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China

2 Department of Acupuncture, Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150001, China

Corresponding author: ZHANG M, E-mail: 13845088833@139.com

Conflicts of interest   None.

Received  2026-01-30
Accepted  2026-04-16
DOI: 10.12015/issn.1674-8034.2026.05.019
DOI:10.12015/issn.1674-8034.2026.05.019.

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