Share:
Share this content in WeChat
X
Review
Advances in the application of flexible MRI coils in head and neck imaging
LU Xiaoping  WANG Yun  WANG Xiao  CHEN Yu  ZHANG Zhuhua  XUE Huadan  JIN Zhengyu 

DOI:10.12015/issn.1674-8034.2026.05.028.


[Abstract] The head and neck region has complex anatomical structures with irregular morphology, adjacent to multiple groups of delicate soft tissue structures and important neurovascular bundles, which imposes extremely high requirements on the soft tissue contrast and spatial resolution of magnetic resonance imaging (MRI). Traditional rigid MRI coils have inherent limitations such as poor anatomical fit, insufficient signal-to-noise ratio (SNR), and low patient examination tolerance, which have become the core bottleneck restricting high-resolution imaging and precise diagnosis and treatment of the head and neck. At present, there is still a lack of systematic sorting and in-depth review of MRI flexible coils in the field of head and neck imaging. This paper systematically expounds the research progress of MRI flexible coils in design principle, material innovation and structural optimization, compares the core performance differences between flexible coils and traditional rigid coils, sorts out the clinical application status of flexible coils in imaging of each subregion of the head and neck, analyzes the core problems existing in current technology research and development and clinical translation, and prospects the future development direction. The purpose of this paper is to provide a reference for the technical research and development, clinical promotion and standardized application of head and neck MRI flexible coils, and to provide new ideas of hardware technology for precise diagnosis and treatment of head and neck diseases.
[Keywords] magnetic resonance imaging;flexible coil;head and neck examination;signal-to-noise ratio;high-resolution imaging

LU Xiaoping   WANG Yun   WANG Xiao   CHEN Yu*   ZHANG Zhuhua   XUE Huadan   JIN Zhengyu  

Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China

Corresponding author: CHEN Y, E-mail: bjchenyu@126.com

Conflicts of interest   None.

Received  2026-01-04
Accepted  2026-04-15
DOI: 10.12015/issn.1674-8034.2026.05.028
DOI:10.12015/issn.1674-8034.2026.05.028.

[1]
JULIANO A F, HUEY N, ROMO L V, et al. Why 2D matters: comparative evaluation of 2D and 3D T1-weighted imaging of the skull base and neck[J]. AJNR Am J Neuroradiol, 2026, 47(1): 131-141. DOI: 10.3174/ajnr.A8887.
[2]
KAZA E, GUENETTE J P, GUTHIER C V, et al. Image quality comparisons of coil setups in 3T MRI for brain and head and neck radiotherapy simulations[J/OL]. J Appl Clin Med Phys, 2022, 23(12): e13794 [2026-01-03]. https://pubmed.ncbi.nlm.nih.gov/36285814/. DOI: 10.1002/acm2.13794.
[3]
ABEL F, TAN E T, LUNENBURG M, et al. Flexible array coil for cervical and extraspinal (FACE) MRI at 3.0 Tesla[J/OL]. Phys Med Biol, 2023, 68(21): 215011 [2026-01-03]. https://pubmed.ncbi.nlm.nih.gov/37816375/. DOI: 10.1088/1361-6560/ad0217.
[4]
KANG Y J, CHEN Y L, FANG J M, et al. Performance of a flexible 12-channel head coil in comparison to commercial 16- and 24-channel rigid head coils[J]. Magn Reson Med Sci, 2022, 21(4): 623-631. DOI: 10.2463/mrms.mp.2021-0084.
[5]
ZHENG L, ZHOU T T, YUAN H, et al. Comparative study on non inferiority of MRI knee joint 8 channel hard coil and 16 channel flexible coil[J]. J Pract Radiol, 2024, 40(6): 994-997. DOI: 10.3969/j.issn.1002-1671.2024.06.031.
[6]
WANG B L, SIDDIQ S S, WALCZYK J, et al. A flexible MRI coil based on a cable conductor and applied to knee imaging[J/OL]. Sci Rep, 2022, 12(1): 15010 [2026-01-03]. https://pubmed.ncbi.nlm.nih.gov/36056131/. DOI: 10.1038/s41598-022-19282-6.
[7]
MOTOVILOVA E, CHING T, VINCENT J, et al. Dual-channel stretchable, self-tuning, liquid metal coils and their fabrication techniques[J/OL]. Sensors (Basel), 2023, 23(17): 7588 [2026-01-03]. https://pubmed.ncbi.nlm.nih.gov/37688046/. DOI: 10.3390/s23177588.
[8]
ZAMARAYEVA A M, GOPALAN K, COREA J R, et al. Custom, spray coated receive coils for magnetic resonance imaging[J/OL]. Sci Rep, 2021, 11(1): 2635 [2026-01-03]. https://pubmed.ncbi.nlm.nih.gov/33514816/. DOI: 10.1038/s41598-021-81833-0.
[9]
MOTOVILOVA E, TAN E T, TARACILA V, et al. Stretchable self-tuning MRI receive coils based on liquid metal technology (LiquiTune)[J/OL]. Sci Rep, 2021, 11(1): 16228 [2026-01-03]. https://pubmed.ncbi.nlm.nih.gov/34376703/. DOI: 10.1038/s41598-021-95335-6.
[10]
MUÑOZ F, LIM Y, CUI S X, et al. Evaluation of a novel 8-channel RX coil for speech production MRI at 0.55 T[J]. MAGMA, 2023, 36(3): 419-426. DOI: 10.1007/s10334-022-01036-0.
[11]
ZHOU S, LI J Y, ZHU X G, et al. Initial clinical experience of surface guided stereotactic radiation therapy with open-face mask immobilization for improving setup accuracy: a retrospective study[J/OL]. Radiat Oncol, 2022, 17(1): 104 [2026-01-03]. https://pubmed.ncbi.nlm.nih.gov/35659685/. DOI: 10.1186/s13014-022-02077-4.
[12]
YE F, WEN X X, YING W F, et al. Comparison of magnetic resonance imaging quality between hard and soft coils of shoulder joint[J]. Chin Imaging J Integr Tradit West Med, 2022, 20(5): 474-478. DOI: 10.3969/j.issn.1672-0512.2022.05.018.
[13]
COSTA G, PAULIDES M M, GÜLER S, et al. Less is more Performance of loops without distributed capacitors for 7 T MRI applications[J/OL]. Magn Reson Imaging, 2025, 121: 110420 [2026-01-03]. https://pubmed.ncbi.nlm.nih.gov/40368254/. DOI: 10.1016/j.mri.2025.110420.
[14]
DARNELL D, TRUONG T K, SONG A W. Recent advances in radio-frequency coil technologies: flexible, wireless, and integrated coil arrays[J]. J Magn Reson Imaging, 2022, 55(4): 1026-1042. DOI: 10.1002/jmri.27865.
[15]
KWOK W E. Basic principles of and practical guide to clinical MRI radiofrequency coils[J]. Radiographics, 2022, 42(3): 898-918. DOI: 10.1148/rg.210110.
[16]
NOHAVA L, OBERMANN M, FRASS-KRIEGL R, et al. A modular system of flexible receive-only coil arrays for 3 T Magnetic Resonance Imaging[J]. Z Med Phys, 2025, 35(2): 193-203. DOI: 10.1016/j.zemedi.2023.05.002.
[17]
THOMPSON E R, CHEN L W, MILLER A J V. Flexible copper foil sheet receive coil array for MRI[J/OL]. medRxiv, 2024:2024.09.05.24313135 [2026-01-03]. https://www.medrxiv.org/content/10.1101/2024.09.05.24313135v1.full.pdf. DOI: 10.1101/2024.09.05.24313135.
[18]
LU M, SUN C W, JIANG X Y, et al. Flexible and shape-adjustable coaxial capacitor (COCA) coils for ultrahigh field MRI: a comparative analysis with rigid coils[J/OL]. J Magn Reson, 2025, 380: 107955 [2026-01-03]. https://pubmed.ncbi.nlm.nih.gov/40885000/. DOI: 10.1016/j.jmr.2025.107955.
[19]
RUYTENBERG T, WEBB A, ZIVKOVIC I. A flexible five-channel shielded-coaxial-cable (SCC) transceive neck coil for high-resolution carotid imaging at 7T[J]. Magn Reson Med, 2020, 84(3): 1672-1677. DOI: 10.1002/mrm.28215.
[20]
TAN W L, ZHAN S H, KANG Y J, et al. Study of flexible and hard head coils on the quality of imaging[J]. Chin Comput Med Imaging, 2017, 23(6): 575-579. DOI: 10.3969/j.issn.1006-5741.2017.06.020.
[21]
TESFAI A S, VOLLMER A, ÖZEN A C, et al. Inductively coupled intraoral flexible coil for increased visibility of dental root canals in magnetic resonance imaging[J]. Invest Radiol, 2022, 57(3): 163-170. DOI: 10.1097/RLI.0000000000000826.
[22]
CHEN Y L, KANG Y J, TAN W L, et al. The improved imaging performance in MRS by the flexible head coil with 12 channels for scalp acupuncture[J]. Chin Imaging J Integr Tradit West Med, 2021, 19(1): 19-23. DOI: 10.3969/j.issn.1672-0512.2021.01.005.
[23]
GONG Z G, ZHAN S H, KONG Y N, et al. Application value of high field flexible coil in craniocerebral imaging quality[J]. Radiol Pract, 2020, 35(4): 555-559. DOI: 10.13609/j.cnki.1000-0313.2020.04.030.
[24]
VOSKUILEN L, DE HEER P, VAN DER MOLEN L, et al. A 12-channel flexible receiver coil for accelerated tongue imaging[J]. Magn Reson Mater Phys Biol Med, 2020, 33(4): 581-590. DOI: 10.1007/s10334-019-00824-5.
[25]
WEI Z D, ZHANG Z L, CHEN Q Y, et al. Open-transmit and flexible receiver array for high resolution ultrahigh-field fMRI of the human sensorimotor cortex[J/OL]. Commun Biol, 2025, 8(1): 482 [2026-01-03]. https://pubmed.ncbi.nlm.nih.gov/40121362/. DOI: 10.1038/s42003-025-07866-7.
[26]
ZHANG Q, ZHU H Q, WANG K, et al. Improving intracranial arteriosclerosic stenosis MRI using wireless resonator array inserts[J/OL]. Magn Reson Imaging, 2025, 123: 110497 [2026-01-03]. https://pubmed.ncbi.nlm.nih.gov/40816610/. DOI: 10.1016/j.mri.2025.110497.
[27]
ALAM W, REINEKE S, RAJA VISWANATH M, et al. A flexible 16-channel custom coil array for accelerated imaging of upper and infraglottic airway at 3 T[J]. Magn Reson Med, 2023, 89(5): 2117-2130. DOI: 10.1002/mrm.29559.
[28]
LEE W, STICKLE Y, FOLLANTE C, et al. A 60-channel high-density flexible receive array for pediatric abdominal MRI[J]. Magn Reson Med, 2025, 93(6): 2655-2666. DOI: 10.1002/mrm.30456.
[29]
TAVAF N, LAGORE R L, JUNGST S, et al. A self-decoupled 32-channel receive array for human-brain MRI at 10.5 T[J]. Magn Reson Med, 2021, 86(3): 1759-1772. DOI: 10.1002/mrm.28788.
[30]
VLIEM J, XIAO Y, WENZ D, et al. Twisted pair transmission line coil-a flexible, self-decoupled and robust element for 7 T MRI[J/OL]. Magn Reson Imaging, 2024, 108: 146-160 [2026-01-03]. https://pubmed.ncbi.nlm.nih.gov/38364973/. DOI: 10.1016/j.mri.2024.02.007.
[31]
Chinese Thoracic Society. Guidelines for the diagnosis and treatment of obstructive sleep apnea in adults (2025)[J]. Chin J Tuberc Respir Dis, 2026, 49(3): 264-296. DOI: 10.3760/cma.j.cn112147-20251108-00694.
[32]
National Cancer Center, Laryngeal Cancerexpert Committee Of National Cancer Quality Control Center. Quality control index for standardized diagnosis and treatment of laryngeal cancer in China (2022 edition)[J]. Chin J Oncol, 2022, 44(12): 1235-1241. DOI: 10.3760/cma.j.cn112152-20220816-00558.
[33]
GUO M, ZHANG T, LI B J. Progress of magnetic resonance imaging in swallowing and dysphagia[J]. Neural Inj Funct Reconstr, 2025, 20(1): 37-40, 48. DOI: 10.16780/j.cnki.sjssgncj.20230321.
[34]
BAE K, JEON K N, HWANG M J, et al. Application of highly flexible adaptive image receive coil for lung MR imaging using zero TE sequence: comparison with conventional anterior array coil[J/OL]. Diagnostics, 2022, 12(1): 148 [2026-01-03]. https://pubmed.ncbi.nlm.nih.gov/35054316/. DOI: 10.3390/diagnostics12010148.
[35]
SONG C H, CHEN Q Y, CHE S, et al. Research progress of ultra-flexible radiofrequency receiver coils for magnetic resonance imaging[J]. Life Sci Instrum, 2022, 20(2): 4-16. DOI: 10.11967/2022200401.
[36]
ZHAO H Y, CHEN Z, WANG S, et al. Advances in the application of carotid magnetic resonance imaging for carotid atherosclerotic disease[J]. Chin J Vasular Surg, 2025, 10(2): 136-141. DOI: 10.3760/cma.j.cn101411-20250409-00044.
[37]
DE BUCK M H S, KENT J L, JEZZARD P, et al. Head-and-neck multichannel B1+ mapping and RF shimming of the carotid arteries using a 7T parallel-transmit head coil[J]. Magn Reson Med, 2024, 91(1): 190-204. DOI: 10.1002/mrm.29845.
[38]
LUDWIG U, EISENBEISS A K, SCHEIFELE C, et al. Dental MRI using wireless intraoral coils[J/OL]. Sci Rep, 2016, 6: 23301 [2026-01-03]. https://pubmed.ncbi.nlm.nih.gov/27021387/. DOI: 10.1038/srep23301.
[39]
OZEN A C, IDIYATULLIN D, ADRIANY G, et al. Design of an intraoral dipole antenna for dental applications[J]. IEEE Trans Biomed Eng, 2021, 68(8): 2563-2573. DOI: 10.1109/TBME.2021.3055777.
[40]
ÖZEN A C, ILBEY S, JIA F, et al. An improved intraoral transverse loop coil design for high-resolution dental MRI[J]. Magn Reson Med, 2023, 90(4): 1728-1737. DOI: 10.1002/mrm.29744.
[41]
FOURNEL A, IANNILLI E, FERDENZI C, et al. A methodological investigation of a flexible surface MRI coil to obtain functional signals from the human olfactory bulb[J/OL]. J Neurosci Methods, 2020, 335: 108624 [2026-01-03]. https://pubmed.ncbi.nlm.nih.gov/32032715/. DOI: 10.1016/j.jneumeth.2020.108624.
[42]
WANG S J, JIANG H, WANG F F, et al. Improved ability of demonstrating ocular masses on 3.0 T MR scanner combined with an 8-channel eye surface phased array coil: a multi-center study[J]. Chin J Radiol, 2023, 57(1): 41-47. DOI: 10.3760/cma.j.cn112149-20220307-00208.
[43]
HAGEMAN K N, CHOW M R, ROBERTS D C, et al. Low-noise magnetic coil system for recording 3-dimensional eye movements[J/OL]. IEEE Trans Instrum Meas, 2021, 70: 1-9 [2026-01-03]. https://pubmed.ncbi.nlm.nih.gov/33776080/. DOI: 10.1109/tim.2020.3020682.
[44]
LU M, YANG X Y, MOORE J, et al. Low-cost and detunable wireless resonator glasses for enhanced eye MRI with concurrent high-quality whole brain MRI[EB/OL]. 2025: arXiv: 2509.08797. https://arxiv.org/abs/2509.08797
[45]
AHMED M, SCHMIDT M, SOHAIB A, et al. The value of magnetic resonance imaging in target volume delineation of base of tongue tumours: a study using flexible surface coils[J]. Radiother Oncol, 2010, 94(2): 161-167. DOI: 10.1016/j.radonc.2009.12.021.
[46]
CHAUVEL M, TESSIER C, VENKATASAMY A, et al. Cine-MRI of deglutition: a systematic review[J]. Dysphagia, 2025, 40(4): 700-710. DOI: 10.1007/s00455-024-10797-w.
[47]
PIETRAGALLA M, GATTUSO E, NARDI C, et al. CT and MRI key features of benign tumors and tumor-like lesions of the tongue: a pictorial review[J/OL]. Cancers, 2025, 17(10): 1695 [2026-01-03]. https://pubmed.ncbi.nlm.nih.gov/40427192/. DOI: 10.3390/cancers17101695.
[48]
SANIOUR I, ROBB F J L, TARACILA V, et al. Characterization of a low-profile, flexible, and acoustically transparent receive-only MRI coil array for high sensitivity MR-guided focused ultrasound[J/OL]. IEEE Access, 2022, 10: 25062-25072 [2026-01-03]. https://pubmed.ncbi.nlm.nih.gov/35600672/. DOI: 10.1109/access.2022.3154824.
[49]
ZHANG S, LI G H, WU L. Design and verification of flexible and elastic coil for the head of wearable MRI device[J]. Chin J Magn Reson Imaging, 2022, 13(2): 62-68. DOI: 10.12015/issn.1674-8034.2022.02.013.
[50]
RAN Y L, ZHANG Q, LI Z X, et al. Advances in MRI wireless coil[J]. Chin J Magn Reson Imaging, 2025, 16(10): 229-234. DOI: 10.12015/issn.1674-8034.2025.10.036.
[51]
WAKS M, LAGORE R L, AUERBACH E, et al. RF coil design strategies for improving SNR at the ultrahigh magnetic field of 10.5T[J]. Magn Reson Med, 2025, 93(2): 873-888. DOI: 10.1002/mrm.30315.

PREV Research progress on predicting molecular subtypes of adult-type diffuse gliomas using image-based artificial intelligence
NEXT Research progress on MRI radiomics in predicting the efficacy of neoadjuvant chemotherapy for breast cancer
  



Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn