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• Clinical Article •
The correlation between the distribution and signal intensity of middle cerebral artery atherosclerotic plaques and acute infarction: a 3.0 T high-resolution MRI study
ZHANG Dan-feng  CHEN Hui-you  ZHANG Wei-dong  SUN Jun  MAO Cun-nan  SU Wen  WANG Peng  YIN Xin-dao 

DOI:10.12015/issn.1674-8034.2017.01.002.


[Abstract] Objective: To investigate the correlation between the distribution and signal intensity of middle cerebral artery (MCA) atherosclerotic plaques and acute infraction using high-resolution magnetic resonance imaging.Materials and Methods: Thirty-two consecutive symptomatic patients with atherosclerotic MCA stenosis were imaged with a 3.0 T magnetic resonance scanner. The HR MRI protocol included T1-weighted, T2-weighted black blood imaging. The patients were divided into acute infarction group and non-acute infarction group, according to hyperintense on DWI or not. The locations of plaques were classified into ventral wall, inferior wall, dorsal wall, superior wall. Signal intensity of plaques were recorded as hyperintense or mixed singal intense.Results: Thirty-two cases were enrolled. 13 plaques were located at the ventral wall, 7 at the inferior wall, 4 at the dorsal wall, 4 at the superior wall, and 4 with lumen occlusion. The acute infarction in corresponding place were 2, 2, 3, 4. The plaques located at dorsal or superior wall were more susceptible to acute infarction (P=0.002). There were 8 plaques with hyperintense or mixed singal intense (SI) on T1WI or T2WI in acute infarction group, while 2 plaques like that in non-acute infarction group, the difference had statistical significance (P=0.021).Conclusions: Middle cerebral artery atherosclerotic plaques have certain tendency to locate at ventral and inferior wall, but plaques at dorsal or superior wall were more susceptible to acute infarction . The plaques with hyperintense or mixed singal intense were more likely to occur in acute infarction cases.
[Keywords] Magnetic resonance imaging；Middle cerebral artery；Plaque, atherosclerotic；Brain infarction

ZHANG Dan-feng Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China

CHEN Hui-you Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China

ZHANG Wei-dong Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China

SUN Jun Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China

MAO Cun-nan Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China

SU Wen Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China

WANG Peng Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China

YIN Xin-dao* Department of Radiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China

*Correspondence to: Yin XD, E-mail: y.163yy@163.com

Conflicts of interest   None.

Received  2016-09-18
Accepted  2016-11-28
DOI: 10.12015/issn.1674-8034.2017.01.002
DOI:10.12015/issn.1674-8034.2017.01.002.

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