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• Clinical Article •
Cardiac magnetic resonance imaging as a diagnostic tool in viral myocarditis with the main symptoms of acute coronary syndrome
RAN Hua  WANG Zheng-zhong  HE Yi  GAO Wan-chun  SHI Ai-jun  QU Jia-quan 

DOI:10.12015/issn.1674-8034.2017.08.004.


[Abstract] Objective: To evaluate the value of cardiac magnetic resonance imaging in the diagnosis of viral myocarditis with the main symptoms of acute coronary syndrome.Materials and Methods: Sixteen cases of highly suspected acute viral myocarditis with negative coronary angiography and five cases of ischemic heart disease as the control were included into this study from January of 2013 to December of 2016 in the department of cardiology, Chongqing Qianjiang central hospital; all the selected patients underwent electrocardiogram-gated magnetic resonance imaging with the scan sequences including T2 weighted imaging (T2WI), turbo FLASH sequence, early gadolinium enhanced (EGE) ratio and late gadolinium enhanced (LGE) sequence, and the data of above sequences were collected and statistically analysed.Results: The scores of T2WI, LGE and overall Lake Louise Criteria significantly increased in viral myocarditis with the main symptoms of acute coronary syndrome comparing to the control by using cardiac magnetic resonance (P=0.021, 0.011, 0.002); receiver operating characteristic curves showed that the best cut-off value of Lake Lewis Criteria score was 6.12, the sensitivity was 93.8%, specificity was 80%; comparing with Turbo FLASH sequence, EGE ratio, LGE, and T2WI, diagnostic efficacy of Lake Lewis Criteria score was balanced; the specificity of LGE was 100%, and the sensitivity of T2WI was 93.8%.Conclusion: Lake Lewis criteria may be an effective and non-invasive tool for the diagnosis of viral myocarditis with the main symptoms of acute coronary syndrom; and MRI-LGE sequence with good specificity and MRI-T2WI sequence with good sensitivity could be used for the differential diagnosis of ischemic heart disease.
[Keywords] Magnetic resonance imaging；Myocarditis；Acute coronary syndrome；Differential diagnosis

RAN Hua Department of Cardiology, Qianjiang Central Hospital of Chongqing, Chongqing 409000, China

WANG Zheng-zhong Department of Cardiology, Qianjiang Central Hospital of Chongqing, Chongqing 409000, China

HE Yi Department of Cardiology, Qianjiang Central Hospital of Chongqing, Chongqing 409000, China

GAO Wan-chun Department of Radiology, Qianjiang Central Hospital of Chongqing, Chongqing 409000, China; School of Medical Imaging, Jishou University, Jishou 416000, China

SHI Ai-jun Department of Radiology, Qianjiang Central Hospital of Chongqing, Chongqing 409000, China; School of Medical Imaging, Jishou University, Jishou 416000, China

QU Jia-quan* Department of Radiology, Qianjiang Central Hospital of Chongqing, Chongqing 409000, China; School of Medical Imaging, Jishou University, Jishou 416000, China

*Correspondence to: Qu JQ, E-mail: honpher@jsu.edu.cn

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Scientific Research Project of Chongqing Science and Technology Commission No. cstc2015shms-ztzx0027 Project of Independent Experimental No. JDDL2016001
Received  2017-04-19
Accepted  2017-06-27
DOI: 10.12015/issn.1674-8034.2017.08.004
DOI:10.12015/issn.1674-8034.2017.08.004.

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