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• Clinical Article •
Comparative study of T2 FLAIR enhancement sequence and T1WI- 3D-TFE enhancement sequence in diagnosis of tuberculous meningitis
ZHENG Guangping  WANG Lifei  YUN Yongxing  LU Puxuan  WEI Fangjun  ZHANG Hui  LUO Jieqi  HUANG Mingyong 

Cite this article as: Zheng GP, Wang LF, Yun YX, et al. Comparative study of T2 FLAIR enhancement sequence and T1WI-3D-TFE enhancement sequence in diagnosis of tuberculous meningitis. Chin J Magn Reson Imaging, 2019, 10(12): 895-898. DOI:10.12015/issn.1674-8034.2019.12.004.


[Abstract] Objective: A comparative study of the clinical value of T2 FLAIR enhancement sequence and T1WI-3D-TFE enhancement sequence in the diagnosis of tuberculous meningitis.Materials and Methods: Thirty-two patients with tuberculous meningitis were studied prospectively. After routine brain MRI scan, T1WI-3D-TFE enhanced scan was performed, and then T2 FLAIR enhanced scan was performed. The images were analyzed by two senior diagnostic doctors. To compare the display degree of T1WI-3D-TFE enhancement and T2 FLAIR enhancement on cerebral parenchymal and leptomeningeal lesions, statistical methods were used to test the two groups of binary data χ2, P<0.05 was statistically significant.Results: T2 FLAIR enhancement showed 85.0% and 92.0% of the cerebral parenchymal and leptomeningeal lesions, and T1WI- 3D-TFE enhancement showed 58.2% and 36.0% of the cerebral parenchymal and leptomeningeal lesions T2 FLAIR enhancement showed a higher display rate than T1WI-3D-TFE enhancement. Statistical results showed that T1WI-3D-TFE enhancement and T2 FLAIR enhancement showed significant differences in the degree of displaying cerebral parenchymal and leptomeningeal lesions.Conclusions: The clinical value of T2 FLAIR enhancement sequence in diagnosis of tuberculous meningitis is better than that of T1WI-3D-TFE enhancement sequence. T2 FLAIR enhancement sequence can better show the number and extent of brain parenchyma and leptomeningeal lesions.
[Keywords] tuberculosis；leptomeninges；meningitis；magnetic resonance imaging

ZHENG Guangping Department of Radiology, the Third People’s Hospital of Shenzhen, Shenzhen 518112, China

WANG Lifei * Department of Radiology, the Third People’s Hospital of Shenzhen, Shenzhen 518112, China

YUN Yongxing Department of Radiology, the Third People’s Hospital of Shenzhen, Shenzhen 518112, China

LU Puxuan Department of Radiology, the Third People’s Hospital of Shenzhen, Shenzhen 518112, China

WEI Fangjun Department of Radiology, the Third People’s Hospital of Shenzhen, Shenzhen 518112, China

ZHANG Hui Department of Radiology, the Third People’s Hospital of Shenzhen, Shenzhen 518112, China

LUO Jieqi Department of Radiology, the Third People’s Hospital of Shenzhen, Shenzhen 518112, China

HUANG Mingyong Department of Radiology, the Third People’s Hospital of Shenzhen, Shenzhen 518112, China

*Correspondence to: Wang LF, E-mail: wanglf007n@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Sanming Project of Medicine in Shenzhen No. SZSM201612053
Received  2019-03-14
DOI: 10.12015/issn.1674-8034.2019.12.004
Cite this article as: Zheng GP, Wang LF, Yun YX, et al. Comparative study of T2 FLAIR enhancement sequence and T1WI-3D-TFE enhancement sequence in diagnosis of tuberculous meningitis. Chin J Magn Reson Imaging, 2019, 10(12): 895-898. DOI:10.12015/issn.1674-8034.2019.12.004.

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