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• Clinical Article •
Quantitative assessment of MRI T1rho imaging for lumbar disc degeneration in the low back pian
LI Dan  WANG Lixia  WU Wenjun  KONG Xiangquan  LIU Dingxi 

Cite this article as: Li D, Wang LX, Wu WJ, et al. Quantitative assessment of MRI T1rho imaging for lumbar disc degeneration in the low back pian. Chin J Magn Reson Imaging, 2019, 10(12): 904-907. DOI:10.12015/issn.1674-8034.2019.12.006.


[Abstract] Objective: To investigate the quantitative diagnostic value of MRI T1rho value in low back pain with lumbar intervertebral disc degeneration.Materials and Methods: Totally 38 low back pain patients and 28 asymptomatic volunteers underwent lumbar MRI examination. Lumbar sagittal T2WI and sagittal T1rho images were obtained. Pfirrmann grades of all lumbar discs were evaluated and T1rho values of nucleus pulposus (NP) were measured. The differences of T1rho values between the low back pain and volunteers at different disc levels of the lumbar disc were compared, and the correlation between T1rho values and Pfirrmann grades, age and BMI were analyzed.Results: Significant difference existed in NP T1rho values at different disc levels of the lumbar disc between the low back pain and volunteers (P<0.01), and the T1rho values of L4/5 and L5/S1 disc were significantly lower than L1/2 and L2/3 disc in the low back pain (P<0.05). The NP T1rho values of Pfirrmann Ⅰ-Ⅳ were (141.5±9.8) ms, (117.1±13.0) ms, (85.6±13.9) ms, (60.5±10.5) ms and the T1 rho value of lumbar disc had a negative correlation with Pfirrmann greeds (r=-0.86, P<0.05), significant difference existed in T1rho values between each Pfirrmann grade (P<0.01). The T1rho value of each lumbar disc in NP had a negative correlation with age and BMI (r=-0.63, P<0.01 and r=-0.33, P<0.01).Conclusions: MRI T1rho imaging is feasible to assess the degree of intervertebral disc degeneration in quantitative, and it has the clinic value in diagnosis of early intervertebral disc degeneration.
[Keywords] magnetic resonance imaging；low back pain；lumbar intervertebral disc degeneration；quantitative assessment；Pfirrmann grades

LI Dan Department of Radiology, Union Hospital Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430022, China

WANG Lixia * Department of Radiology, Union Hospital Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430022, China

WU Wenjun Department of Radiology, Union Hospital Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430022, China

KONG Xiangquan Department of Radiology, Union Hospital Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430022, China

LIU Dingxi Department of Radiology, Union Hospital Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430022, China

*Correspondence to: Wang LX, E-mail:lisa2003627@163.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This work was part of Natural Science Foundation of Hubei Province No.2017CFB708 Innovative Research Foundation of Huazhong University of Science and Technology No.2016YXMS234 Scientific Research Foundation of Wuhan Union Hospital No.02.03.2018-224
Received  2019-08-22
DOI: 10.12015/issn.1674-8034.2019.12.006
Cite this article as: Li D, Wang LX, Wu WJ, et al. Quantitative assessment of MRI T1rho imaging for lumbar disc degeneration in the low back pian. Chin J Magn Reson Imaging, 2019, 10(12): 904-907. DOI:10.12015/issn.1674-8034.2019.12.006.

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