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Research status and progress of HIV-related neurological cognitive dysfunction syndrome based on MRI
GAO Yuxun  LI Hongjun 

Cite this article as: Gao YX, Li HJ. Research status and progress of HIV-related neurological cognitive dysfunction syndrome based on MRI[J]. Chin J Magn Reson Imaging, 2021, 12(1): 65-69. DOI:10.12015/issn.1674-8034.2021.01.014.


[Abstract] Human immunodeficiency virus (HIV), or acquired immunodeficiency syndrome (AIDS) virus, is a virus that causes defects in the human immune system. Combination antiretroviral therapy (cART) has transformed HIV from a rapidly fatal disease to a more manageable chronic disease. Therefore, the life expectancy of HIV-infected (HIV) individuals receiving cART is almost as long as that of HIV-uninfected (HIV-) individuals. After infection, HIV enters the brain and can cause HIV-related neurocognitive disease (HAND) after a period of time. Magnetic resonance imaging (MRI) techniques [including magnetic resonance spectroscopy (MRS), structural MRI (sMRI), diffusion tensor imaging (DTI) and functional magnetic resonance imaging (fMRI)] and positron emission tomography (PET) have been used in HIV individuals. This article will introduce in detail the application and research progress of various magnetic resonance imaging technologies and brain networks in HAND.
[Keywords] human immunodeficiency virus；combined antiretroviral therapy；cognitive impairment；magnetic resonance imaging；neuroimaging；brain network

GAO Yuxun   LI Hongjun*  

Department of Radiology, Beijing Youan Hospital, Capital Medical University, Beijing 100071, China

*Corresponding author: Li HJ, E-mail: lihongjun00113@126.com

Conflicts of interest   None.

ACKNOWLEDGMENTS  This article is supported by the National Natural Science Found of China No. 61936013
Received  2020-10-15
Accepted  2020-11-30
DOI: 10.12015/issn.1674-8034.2021.01.014
Cite this article as: Gao YX, Li HJ. Research status and progress of HIV-related neurological cognitive dysfunction syndrome based on MRI[J]. Chin J Magn Reson Imaging, 2021, 12(1): 65-69. DOI:10.12015/issn.1674-8034.2021.01.014.

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