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• CLINICAL ARTICLE •
Value of 3.0 T MR diffusion-weighted imaging and ROC curve in diagnosis of lymph node metastasis in patients with prostate cancer
FU Zhao  CHEN Yanqing  ZHAO Chunli  HUANG Tao  OU Ning  MA Longbai 

Cite this article as: Fu Z, Chen YQ, Zhao CL, et al. Value of 3.0 T MR diffusion-weighted imaging and ROC curve in diagnosis of lymph node metastasis in patients with prostate cancer[J]. Chin J Magn Reson Imaging, 2021, 12(2): 49-51. DOI:10.12015/issn.1674-8034.2021.02.011.


[Abstract] Objective To explore the value of diffusion-weighted imaging (DWI) in the diagnosis of metastatic and non-metastatic lymph nodes of prostate cancer. Materials andMethods Fifty patients with prostate cancer who underwent lymph node dissection were analyzed retrospectively. All patients underwent conventional MRI and DWI before operation. Three hundred and three lymph nodes were removed. The difference of apparent diffusion coefficient(ADC) between metastatic and non-metastatic lymph nodes was compared. Receiver operating characteristic (ROC) curve was drawn, and the cutoff value for metastatic lymph nodes detection was determined, the sensitivity, specificity and accuracy were calculated.Results The ADC of metastatic lymph nodes (0.816±0.105)×10-3 mm2/s was lower than that of non-metastatic lymph nodes (1.298±0.251)×10-3 mm2/s, P=0.025. ROC curve showed that the ADC value for the best critical point of diagnosis for metastatic lymph nodes was 0.970×10-3 mm2/s. The sensitivity was 94.5%, specificity was 74.5%, accuracy was 67.0%.Conclusions Value of ADC is helpful in differentiating metastatic and non-metastatic lymph nodes in prostate cancer.
[Keywords] prostate cancer；diffusion-weighted imaging；apparent diffusion coefficient；lymph node metastasis；receiver operating characteristic curve

FU Zhao*   CHEN Yanqing   ZHAO Chunli   HUANG Tao   OU Ning   MA Longbai  

Department of Radiology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China

Fu Z, E-mail: 331010282@qq.com

Conflicts of interest   None.

ACKNOWLEDGENTS This work was part of Health Commission of Guangxi Zhuang Autonomous Region Self-Funded Research Project (No.Z20190037).
Received  2020-04-15
Accepted  2020-06-12
DOI: 10.12015/issn.1674-8034.2021.02.011
Cite this article as: Fu Z, Chen YQ, Zhao CL, et al. Value of 3.0 T MR diffusion-weighted imaging and ROC curve in diagnosis of lymph node metastasis in patients with prostate cancer[J]. Chin J Magn Reson Imaging, 2021, 12(2): 49-51. DOI:10.12015/issn.1674-8034.2021.02.011.

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