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Research progress of neurite direction dispersion and density imaging in Alzheimer's disease
WEI Zhihao  WANG Hong 

Cite this article as: Wei ZH, Wang H. Research progress of neurite direction dispersion and density imaging in Alzheimer's disease[J]. Chin J Magn Reson Imaging, 2021, 12(4): 103-105. DOI:10.12015/issn.1674-8034.2021.04.026.


[Abstract] Neurite direction dispersion and density imaging (NODDI) is a relatively practical diffusion magnetic resonance imaging technique that can be used to quantify the microstructure of nerve dendrites and axons, so as to obtain morphological information of nerve fibers. Compared with diffusion tensor imaging (DTI), which is widely used in clinical practice, these neurite indicators are more specific for the assessment of the microstructure of brain tissue. Alzheimer's disease (AD) is a degenerative disease of the central nervous system characterized by progressive cognitive dysfunction and memory loss. Therefore, NODDI technology can be used to estimate the microstructure of the nervous system of AD patients. The basic principles of NODDI technology and the research progress in AD are reviewed.

WEI Zhihao   WANG Hong*  

Imaging Center of the Second Affiliated Hospital of Xinjiang Medical University, Urumqi 830063, China

Wang H, E-mail: wangh_xj@163.com

Conflicts of interest   None.

This work was part of Natural Science Foundation of Xinjiang Uygur Autonomous Region (No. 2019D01C227, 2020D01C191).
Received  2021-01-06
Accepted  2021-01-28
DOI: 10.12015/issn.1674-8034.2021.04.026
Cite this article as: Wei ZH, Wang H. Research progress of neurite direction dispersion and density imaging in Alzheimer's disease[J]. Chin J Magn Reson Imaging, 2021, 12(4): 103-105. DOI:10.12015/issn.1674-8034.2021.04.026.

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