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• Clinical Article •
Preliminary study on risk model of clinical and MRI features of recurrent acute pancreatitis
TANG Lingling  HUANG Xiaohua  LIU Nian  HU Yuntao  FANG Jie 

Cite this article as: Tang LL, Huang XH, Liu N, et al. Preliminary study on risk model of clinical and MRI features of recurrent acute pancreatitis[J]. Chin J Magn Reson Imaging, 2021, 12(8): 27-32. DOI:10.12015/issn.1674-8034.2021.08.006.


[Abstract] Objective To investigate the clinical and MRI risk factors of the recurrence of acute pancreatitis (AP), and to establish the risk model of clinical imaging features of recurrent acute pancreatitis (RAP), so as to provide the basis for the prevention, diagnosis and treatment of RAP. Materials andMethods A total of 132 patients with AP diagnosed for the first time (AP group) and 86 patients with recurrent AP (RAP group) in the Affiliated Hospital of North Sichuan Medical College from January 2015 to December 2017 were retrospectively collected. The clinical characteristics and MRI imaging data of the two groups were recorded, and the risk factors of the recurrence of AP were analyzed.Results There were significant differences in the ratio of age (P=0.001), gender (P＜0.001) and incidence of hyperlipidemia(P＜0.001) between the RAP group and AP group. There was no significant difference in the ratio of drinking, biochemical indexes of pancreatitis between the two groups (all P＞0.05). The severity of pancreatitis (P＜0.001), MRSI (P=0.001), complication classification (P=0.012), type of pancreaticobiliary junction (P=0.003) and angle of pancreaticobiliary junction (P＜0.001) were statistically different between the two groups. There was no significant difference in the incidence of bile duct stones (P＞0.05). Logistic regression analysis showed that male patients, V-type and B-P-type junction, pancreaticobiliary angle, hyperlipidemia and first-episode of AP as mild or moderate severe were risk factors for RAP, and age was protective factor for RAP.Conclusions MRI features combined with clinical features can predict the recurrence of acute pancreatitis, which can provide the basis for the prevention, diagnosis and treatment of RAP.
[Keywords] acute pancreatitis；magnetic resonance imaging；clinical characteristics

TANG Lingling1, 2   HUANG Xiaohua1   LIU Nian1*   HU Yuntao1   FANG Jie1  

1 Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China

2 Department of Radiology, the Second Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China

Liu N, E-mail: 232402432@qq.com

Conflicts of interest   None.

ACKNOWLEDGMENTS This work was part of Sichuan Science and Technology Program (No.2020088); The Science and Technology Project of the Health Planning Committee of Sichuan (No.19PJ203); Bureau of Science & Technology and Intellectual Property Nanchong City (No. 19SXHZ0255, 19SXHZ0429).
Received  2021-03-23
Accepted  2021-05-31
DOI: 10.12015/issn.1674-8034.2021.08.006
Cite this article as: Tang LL, Huang XH, Liu N, et al. Preliminary study on risk model of clinical and MRI features of recurrent acute pancreatitis[J]. Chin J Magn Reson Imaging, 2021, 12(8): 27-32. DOI:10.12015/issn.1674-8034.2021.08.006.

1
Jagannath S, Garg PK. Recurrent acute pancreatitis: current concepts in the diagnosis and management[J]. Curr Treat Options Gastroenterol, 2018, 16(4): 449-465. DOI: 10.1007/s11938-018-0196-9.
2
Seppänen H, Puolakkainen P. Classification, severity assessment, and prevention of recurrences in acute pancreatitis[J]. Scand J Surg, 2020, 109(1): 53-58. DOI: 10.1177/1457496920910007.
3
Machicado JD, Yadav D. Epidemiology of recurrent acute and chronic pancreatitis: similarities and differences[J]. Dig Dis Sci, 2017, 62(7): 1683-1691. DOI: 10.1007/s10620-017-4510-5.
4
Coté GA, Yadav D, Abberbock JA, et al. Recurrent acute pancreatitis significantly reduces quality of life even in the absence of overt chronic pancreatitis[J]. Am J Gastroenterol, 2018, 113(6): 906-912. DOI: 10.1038/s41395-018-0087-7.
5
Peng L, Peng Y, Pu YQ, et al. Analyses of clinical characteristics and risk factors of 671 cases of recurrent acute pancreatitis[J]. J Pract Med, 2019, 35(18): 2924-2928. DOI: 10.3969/j.issn.1006-5725.2019.18.020.
6
Li XQ, Liu H, Xiao CT, et al. Influence of metabolic syndrome on patients with recurrence of hypertriglyceridemic acute pancreatitis[J]. J Clin Hepatol, 2020, 36(11): 2515-2520. DOI: 10.3969/j.issn.1001-5256.2020.11.023.
7
Liu QY, Abu-El-Haija M, Husain SZ, et al. Risk factors for rapid progression from acute recurrent to chronic pancreatitis in children: report from insppire[J]. J Pediatr Gastroenterol Nutr, 2019, 69(2): 206-211. DOI: 10.1097/MPG.0000000000002405.
8
Ji JT, Zhang D, Xin L, et al. Research progress in diagnosis and treatment of recurrent acute pancreatitis[J]. Chin J Pancreatol, 2016, 16(3): 203-205. DOI: 10.3760/cma.j.issn.1674-1935.2016.03.016.
9
Kuai XL, Ding HF, Zhang JF, et al. Analysis of risk factors of recurrent acute pancreatitis[J]. Chin J Gastroenterol, 2016, 21(12): 729-732. DOI: 10.3969/j.issn.1008-7125.2016.12.007.
10
Wang SY. Correlation analysis between biochemical indicators and the MR severity index in patients with acute pancreatitis and a MRI study about the relation between recurrence of acute pancreatitis and morphological characteristics of pancreaticobiliary[D]. Nanchong: North Sichuan Med College, 2015.
11
Avanesov M, Löser A, Smagarynska A, et al. Clinico-radiological comparison and short-term prognosis of single acute pancreatitis and recurrent acute pancreatitis including pancreatic volumetry[J]. PLoS One, 2018, 13(10): e206062. DOI: 10.1371/journal.pone.0206062.
12
Liu N, Huang XH, Yang XX, et al. The correlation study of the type and angle of pancreaticobiliary junction and recurrent acute pancreatitis[J]. J Pract Radiol, 2020, 36(8): 1253-1256. DOI: 10.3969/j.issn.1002-1671.2020.08.019.
13
Du YQ, Chen QK, Li HY, et al. Chinese guidelines for the management of acute pancreatitis (Shenyang,2019)[J]. J Clin Hepatol, 2019, 35(12): 2706-2711.
14
Xiao B, Xu HB, Jiang ZQ, et al. Current concepts for the diagnosis of acute pancreatitis by multiparametric magnetic resonance imaging[J]. Quant Imaging Med Surg, 2019, 9(12): 1973-1985. DOI: 10.21037/qims.2019.11.10.
15
Xu HX, Huang XH, Liu ML, et a1. Application of MR diffusion kurtosis imaging in the severity grading of acute pancreatitis[J]. Radiol Pract, 2019, 34(2): 167-173. DOI: 10.13609/j.cnki.1000-0313.2019.02.011.
16
Liu N, Huang XH, Zhang XM, et al. The angle of pancreaticobiliary junction correlates with acute pancreatitis: a magnetic resonance cholangiopancreatography study[J]. Quant Imaging Med Surg, 2015, 5(3): 401-406. DOI: 10.3978/j.issn.2223-4292.2015.03.13.
17
Qu FZ, Cao CL, Wang G, et al. Research updates on recurrent pancreatitis[J]. Chin J Hepatobiliary Surg, 2016, 22(6): 422-424. DOI: 10.3760/cma.j.issn.1007-8118.2016.06.018.
18
Petrov MS, Yadav D. Global epidemiology and holistic prevention of pancreatitis[J]. Nat Rev Gastroenterol Hepatol, 2019, 16(3): 175-184. DOI: 10.1038/s41575-018-0087-5.
19
Vipperla K, Somerville C, Furlan A, et al. Clinical profile and natural course in a large cohort of patients with hypertriglyceridemia and pancreatitis[J]. J Clin Gastroenterol, 2017, 51(1): 77-85. DOI: 10.1097/MCG.0000000000000579.
20
Chen Y, Chen TW, Wu CQ, et al. Radiomics model of contrast-enhanced computed tomography for predicting the recurrence of acute pancreatitis[J]. Eur Radiol, 2019, 29(8): 4408-4417. DOI: 10.1007/s00330-018-5824-1.
21
Xiang JX, Hu LS, Liu P, et al. Impact of cigarette smoking on recurrence of hyperlipidemic acute pancreatitis[J]. World J Gastroenterol, 2017, 23(47): 8387-8394. DOI: 10.3748/wjg.v23.i47.8387.
22
Zafrir B, Saliba W, Jubran A, et al. Severe hypertriglyceridemia-related pancreatitis: characteristics and predictors of recurrence[J]. Pancreas, 2019, 48(2): 182-186. DOI: 10.1097/MPA.0000000000001235.
23
Irie S, Anno T, Kawasaki F, et al. Severe hypertriglyceridemia in a subject with disturbed life style and poor glycemic control without recurrence of acute pancreatitis: a case report[J]. BMC Endocr Disord, 2019, 19(1): 92. DOI: 10.1186/s12902-019-0425-9.
24
Ye ML. Establishment of acute pancreatitis database and risk assessment of severity of acute pancreatitis[D]. Luzhou: Southwest Med Univ, 2017.
25
Kim YS, Chang JH, Kim TH, et al. Prolonged hyperamylasemia in patients with acute pancreatitis is associated with recurrence of acute pancreatitis[J]. Medicine (Baltimore), 2020, 99(3): e18861. DOI: 10.1097/MD.0000000000018861.
26
Bian F, Du Y, Gu ZQ, et al. Evaluation of the relationship between biliopancreatic duct interflow typing and incidence of pancreatitis by MRCP[J]. J Pract Med, 2013, 29(2): 287-289. DOI: 10.3969/j.issn.1006-5725.2013.02.050.
27
Bálint ER, Fűr G, Kiss L, et al. Assessment of the course of acute pancreatitis in the light of aetiology: a systematic review and meta-analysis[J]. Sci Rep, 2020, 10(1): 17936. DOI: 10.1038/s41598-020-74943-8.
28
Cho JH, Jeong YH, Kim KH, et al. Risk factors of recurrent pancreatitis after first acute pancreatitis attack: a retrospective cohort study[J]. Scand J Gastroenterol, 2020, 55(1): 90-94. DOI: 10.1080/00365521.2019.1699598.
29
Kim SB, Kim TN, Chung HH, et al. Small gallstone size and delayed cholecystectomy increase the risk of recurrent pancreatobiliary complications after resolved acute biliary pancreatitis[J]. Dig Dis Sci, 2017, 62(3): 777-783. DOI: 10.1007/s10620-016-4428-3.

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