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• Clinical Article •
The value of T1 mapping and ECV in the diagnosis of acute pancreatitis and recurrent acute pancreatitis: a primary study
LU Ming  WANG Chen  YU Jing  CHENG Shenhao  XU Qing 

Cite this article as: Lu M, Wang C, Yu J, et al. The value of T1 mapping and ECV in the diagnosis of acute pancreatitis and recurrent acute pancreatitis: a primary study[J]. Chin J Magn Reson Imaging, 2021, 12(11): 26-30. DOI:10.12015/issn.1674-8034.2021.11.006.


[Abstract] Objective To investigate the diagnostic value of T1 mapping imaging and extracellular volume fraction (ECV) in acute pancreatitis (AP) and recurrent acute pancreatitis (RAP).Materials and Methods: The patients who underwent pancreatic MRI and T1 mapping examination were respectively analyzed between December 2018 and June 2020 in our hospital. The enrolled cases were grouped as AP group (40 cases) and normal control group (22 cases). Additionally, the cases in AP group were divided into two subgroups: single acute pancreatitis (SAP) (20 cases) and RAP (20 cases) according to the frequency of AP attacks. T1 relaxation times before and after enhancement in pancreatic parenchyma (T1pre pancreas and T1post pancreas) and abdominal aorta on the same slice (T1pre blood and T1post blood) were measured and the value of pancreatic enhancement ratio (PER) and ECV were calculated in all patients. The Mann-Whitney U-test and independent t-test were applied to compare the differences of these parameters between AP group and normal control group as well as SAP group and RAP group.Results AP group tend to have higher values of T1pre pancreas, T1post pancreas, PER and ECV [(1145.20±25.90) ms, (473.50±13.20) ms, 0.65±0.00, 0.39±0.00 respectively] than that in normal control group [(802.20±12.20) ms, (434.60±8.40) ms, 0.38±0.00, 0.28±0.00 respectively], which were statistically significant between the two groups (P＜0.05). However, only the value of ECV was statistically significant between SAP group (0.35±0.20) and RAP group (0.41±0.10) (P=0.01).Conclusions T1 mapping parameters and ECV are effective quantitative imaging parameters for diagnosis of acute pancreatitis and recurrent acute pancreatitis.
[Keywords] acute pancreatitis；recurrent acute pancreatitis；T1 mapping imaging；extracellular volume fraction；magnetic resonance imaging

LU Ming   WANG Chen   YU Jing   CHENG Shenhao   XU Qing*  

Department of Radiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China

Xu Q, E-mail: jsxuqing2015@163.com

Conflicts of interest   None.

Received  2021-05-07
Accepted  2021-07-30
DOI: 10.12015/issn.1674-8034.2021.11.006
Cite this article as: Lu M, Wang C, Yu J, et al. The value of T1 mapping and ECV in the diagnosis of acute pancreatitis and recurrent acute pancreatitis: a primary study[J]. Chin J Magn Reson Imaging, 2021, 12(11): 26-30. DOI:10.12015/issn.1674-8034.2021.11.006.

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