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Application of magnetic resonance imaging in the diagnosis and brain stimulation treatment of Parkinson's disease tremor
MA Hang  BAI Yan  WEI Wei  LI Ziqiang  WANG Meiyun 

Cite this article as: Ma H, Bai Y, Wei W, et al. Application of magnetic resonance imaging in the diagnosis and brain stimulation treatment of Parkinson's disease tremor[J]. Chin J Magn Reson Imaging, 2022, 13(1): 143-146. DOI:10.12015/issn.1674-8034.2022.01.033.


[Abstract] Parkinson's disease (PD) is characterized by the dopamine degeneration in substantia nigra and striatum. Its clinical manifestations include motor symptoms tremor, bradykinesia and rigidity, also have additional non-motor symptoms such as depression anxiety, cognitive impairment. Tremor, as one of most common symptoms, the underlying mechanism is still unclear, about three out of four PD patients develop tremor during the course of their disease and tremor-dominant patients generally follow a more benign disease course than non-tremor patients. There is growing evidence that brain stimulation such as deep brain stimulation and transcranial magnetic stimulation has been a treatment option for PD. Recently, magnetic resonance imaging is widely used in the diagnosis and treatment of PD which can provide important information for early diagnosis and treatment effect evaluation from the aspects of structure and function. This paper reviews the application of MRI in the diagnosis of tremor-dominant PD patients and the value of MRI in evaluating the efficacy of brain stimulation therapy.
[Keywords] Parkinson's disease；tremor；medical imaging；magnetic resonance imaging；brain stimulation

MA Hang1, 2   BAI Yan2   WEI Wei2   LI Ziqiang1, 2   WANG Meiyun2*  

1 Xinxiang Medical University, Xinxiang 453003, China

2 Department of Medical Imaging, Henan Provincial People's Hospital, Zhengzhou 450003, China

Wang MY, E-mail: mywang@ha.edu.cn

Conflicts of interest   None.

ACKNOWLEDGMENTS National Key R&D Program Project (No. 2017YFE0103600); National Natural Science Foundation of China (No. 81720108021); Henan Province Medical Science and Technology Research Project (No. SBGJ202003002); Henan Province High-level Talents "Zhongyuan Thousand Talents Plan" Project (No. ZYQR201810117).
Received  2021-07-28
Accepted  2021-11-09
DOI: 10.12015/issn.1674-8034.2022.01.033
Cite this article as: Ma H, Bai Y, Wei W, et al. Application of magnetic resonance imaging in the diagnosis and brain stimulation treatment of Parkinson's disease tremor[J]. Chin J Magn Reson Imaging, 2022, 13(1): 143-146. DOI:10.12015/issn.1674-8034.2022.01.033.

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