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• Clinical Article •
The value of dynamic contrast enhanced-magnetic resonance imaging based on compressed sensing volumetric interpolated breath-hold examination in the differential diagnosis between benign and malignant thyroid nodules
CHEN Jiao  JIANG Liling  LIU Daihong  WU Jian  ZHANG Junbin  ZHANG Jiuquan 

Cite this article as: Chen J, Jiang LL, Liu DH, et al. The value of dynamic contrast enhanced-magnetic resonance imaging based on compressed sensing volumetric interpolated breath-hold examination in the differential diagnosis between benign and malignant thyroid nodules[J]. Chin J Magn Reson Imaging, 2022, 13(4): 38-42. DOI:10.12015/issn.1674-8034.2022.04.007.


[Abstract] Objective To explore the value of dynamic contrast enhanced-magnetic resonance imaging (DCE-MRI) based on compressed sensing volumetric interpolated breath-hold examination (CS-VIBE) in the differential diagnosis between benign and malignant thyroid nodules.Materials and Methods In this retrospective study, the patients with thyroids were enrolled from September 2020 to May 2021 in our hospital. A total of 84 nodules were included, including 43 malignant nodules and 41 benign nodules. All patients were examined by routine MRI and DCE-MRI before the operation. The DCE-MRI parameters including volume transfer constant (Ktrans), rate constant (Kep), extracellular space volume fraction (Ve) and initial area under curve (iAUC) were acquired. The difference of quantitative parameters between benign and malignant thyroid nodules was compared. The binary logistic regression analysis was used to build prediction model. The receiver operating characteristic (ROC) curces were performed to evaluate the diagnostic performance.Results The malignant group had a significantly higher Ktrans value (P＜0.001), Kep value (P＜0.001) and iAUC value (P=0.001) than the benign group. The Ve value was not significantly different between malignant and benign nodules (P=0.177). In the prediction model, the sensitivity and specificity were 83.33% and 73.81%, respectively.Conclusions The DCE-MRI with CS-VIBE had good diagnostic performance in the differential diagnosis between benign and malignant thyroid nodules.
[Keywords] dynamic contrast enhanced；magnetic resonance imaging；compressed sensing volumetric interpolated breath-hold examination；thyroid nodules；differential diagnosis

CHEN Jiao1   JIANG Liling1   LIU Daihong1   WU Jian2   ZHANG Junbin2   ZHANG Jiuquan1*  

1 Department of Radiology, Chongqing University Cancer Hospital, Chongqing 400030, China

2 Head and Neck Cancer Center, Chongqing University Cancer Hospital, Chongqing 400030, China

Zhang JQ, E-mail: zhangjq_radiol@foxmail.com

Conflicts of interest   None.

ACKNOWLEDGMENTS National Natural Science Foundation of China (No. 82071883).
Received  2021-11-16
Accepted  2022-03-16
DOI: 10.12015/issn.1674-8034.2022.04.007
Cite this article as: Chen J, Jiang LL, Liu DH, et al. The value of dynamic contrast enhanced-magnetic resonance imaging based on compressed sensing volumetric interpolated breath-hold examination in the differential diagnosis between benign and malignant thyroid nodules[J]. Chin J Magn Reson Imaging, 2022, 13(4): 38-42. DOI:10.12015/issn.1674-8034.2022.04.007.

[1]
Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries[J]. CA Cancer J Clin, 2021, 71(3): 209-249. DOI: 10.3322/caac.21660.
[2]
Tappouni R, Itri J, McQueen T, et al. ACR TI-RADS: Pitfalls, Solutions, and Future Directions[J]. Radiographics, 2019, 39(7): 2040-2052. DOI: 10.1148/rg.2019190026.
[3]
Wang H, Song B, Ye N, et al. Machine learning-based multiparametric MRI radiomics for predicting the aggressiveness of papillary thyroid carcinoma[J]. Eur J Radiol, 2020, 122: 108755. DOI: 10.1016/j.ejrad.2019.108755.
[4]
Meyer HJ, Wienke A, Surov A. Discrimination between malignant and benign thyroid tumors by diffusion-weighted imaging-A systematic review and meta analysis[J]. Magn Reson Imaging, 2021, 84: 41-57. DOI: 10.1016/j.mri.2021.09.006.
[5]
Paudyal R, Lu Y, Hatzoglou V, et al. Dynamic contrast-enhanced MRI model selection for predicting tumor aggressiveness in papillary thyroid cancers[J]. NMR Biomed, 2020, 33(1): e4166. DOI: 10.1002/nbm.4166.
[6]
Sakat MS, Sade R, Kilic K, et al. The Use of Dynamic Contrast-Enhanced Perfusion MRI in Differentiating Benign and Malignant Thyroid Nodules[J]. Indian J Otolaryngol Head Neck Surg, 2019, 71(Suppl 1): 706-711. DOI: 10.1007/s12070-018-1512-3.
[7]
Zeng J, Cheng Q, Zhang D, et al. Diagnostic Ability of Dynamic Contrast-Enhanced Magnetic Resonance Imaging for Prostate Cancer and Clinically Significant Prostate Cancer in Equivocal Lesions: A Systematic Review and Meta-Analysis[J]. Front Oncol, 2021, 11: 620628. DOI: 10.3389/fonc.2021.620628.
[8]
Partovi S, Sin D, Lu Z, et al. Fast MRI breast cancer screening-Ready for prime time[J]. Clin Imaging, 2020, 60(2): 160-168. DOI: 10.1016/j.clinimag.2019.10.013.
[9]
Seki S, Fujisawa Y, Yui M, et al. Dynamic Contrast-enhanced Area-detector CT vs Dynamic Contrast-enhanced Perfusion MRI vs FDG-PET/CT: Comparison of Utility for Quantitative Therapeutic Outcome Prediction for NSCLC Patients Undergoing Chemoradiotherapy[J]. Magn Reson Med Sci, 2020, 19(1): 29-39. DOI: 10.2463/mrms.mp.2018-0158.
[10]
Li Y, Xia C, Peng W, et al. Dynamic contrast-enhanced MR imaging of rectal cancer using a golden-angle radial stack-of-stars VIBE sequence: comparison with conventional contrast-enhanced 3D VIBE sequence[J]. Abdom Radiol (NY), 2020, 45(2): 322-331. DOI: 10.1007/s00261-019-02225-7.
[11]
Hylton N. Dynamic contrast-enhanced magnetic resonance imaging as an imaging biomarker[J]. J Clin Oncol, 2006, 24(20): 3293-3298. DOI: 10.1200/jco.2006.06.8080.
[12]
Wu MN, Liang LF, Zhang MR, et al. Value of multi-parameter MRI in the diagnosis of thyroid benign and malignant nodules[J]. Chin J Radiol, 2021, 55(7): 710-715. DOI: 10.3760/cma.j.cn112149-20200822-01022.
[13]
Hausmann D, Kreul D, Klarhöfer M, et al. Morphological and functional assessment of the uterus: "one-stop shop imaging" using a compressed-sensing accelerated, free-breathing T1-VIBE sequence[J]. Acta Radiol, 2021, 62(5): 695-704. DOI: 10.1177/0284185120936260.
[14]
Chung MS, Yim Y, Sung JK, et al. CS-VIBE accelerates cranial nerve MR imaging for the diagnosis of facial neuritis: comparison of the diagnostic performance of post-contrast MPRAGE and CS-VIBE[J]. Eur Radiol, 2021, 1(32): 223-233. DOI: 10.1007/s00330-021-08102-6.
[15]
Marzi S, Piludu F, Forina C, et al. Correlation study between intravoxel incoherent motion MRI and dynamic contrast-enhanced MRI in head and neck squamous cell carcinoma: Evaluation in primary tumors and metastatic nodes[J]. Magn Reson Imaging, 2017, 37: 1-8. DOI: 10.1016/j.mri.2016.10.004.
[16]
Xu X, Choi Y, Sung Y, et al. Intravoxel Incoherent Motion MR Imaging in the Head and Neck: Correlation with Dynamic Contrast-Enhanced MR Imaging and Diffusion-Weighted Imaging[J]. Korean J RadioL, 2016, 17(5): 641-649. DOI: 10.3348/kjr.2016.17.5.641.
[17]
Dong H, Kang L, Cheng S, et al. Diagnostic performance of dynamic contrast-enhanced magnetic resonance imaging for breast cancer detection: An update meta-analysis[J]. Thorac Cancer, 2021, 23(12): 3201-3207. DOI: 10.1111/1759-7714.14187.
[18]
Yeo D, Oh S, Jung C, et al. Correlation of dynamic contrast-enhanced MRI perfusion parameters with angiogenesis and biologic aggressiveness of rectal cancer: Preliminary results[J]. J Magn Reson Imaging, 2015, 41(2): 474-480. DOI: 10.1002/jmri.24541.
[19]
Liu YY, Yue B, Sun LL, et al. The value of quantitative parameters of dynamic contrast-enhanced MRI in evaluating the biological behavior of soft tissue tumors[J]. Chin J Radiol, 2020, 54(10): 980-985. DOI: 10.3760/cma.j.cn112149-20200224-00238.
[20]
Yankeelov T, Gore J. Dynamic Contrast Enhanced Magnetic Resonance Imaging in Oncology: Theory, Data Acquisition, Analysis, and Examples[J]. Curr Med Imaging Rev, 2009, 3(2): 91-107. DOI: 10.2174/157340507780619179.
[21]
Song M, Yue Y, Guo J, et al. Quantitative analyses of the correlation between dynamic contrast-enhanced MRI and intravoxel incoherent motion DWI in thyroid nodules[J]. Am J Transl Res, 2020, 12(7): 3984-3992. DOI: eCollection2020.

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