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• Technical Article •
A comparative study on phantom verification of T1 and T2 relaxation values determined by synthetic MRI and conventional mapping methods
LIU Yawen  NIU Haijun  YIN Hongxia  ZHENG Zuofeng  REN Pengling  ZHANG Tingting  ZHAO Pengfei  LÜ Han  WANG Zhenchang 

Cite this article as: Liu YW, Niu HJ, Yin HX, et al. A comparative study on phantom verification of T1 and T2 relaxation values determined by synthetic MRI and conventional mapping methods[J]. Chin J Magn Reson Imaging, 2022, 13(4): 89-93. DOI:10.12015/issn.1674-8034.2022.04.016.


[Abstract] Objective To verify the accuracy and repeatability of the quantitative imaging of longitudinal relaxation time (T1) and transverse relaxation time (T2) relaxation in synthetic MRI.Materials and Methods For a 3.0 T MR device, three phantoms of gray matter, white matter and cerebrospinal fluid were respectively scanned by synthetic MRI and conventional quantitative magnetic resonance imaging (qMRI), and the acquisition was repeated four times. For conventional qMRI, the corresponding T1 and T2 values were obtained by fitting calculation, while for synthetic MRI, the T1 and T2 values were calculated using MAGiC software. Two-way analysis of variance was used to compare phantom values obtained by synthetic MRI and those calculated by conventional mapping methods.Results The results of analysis of variance of T1and T2 showed that there are no significant difference between the synthetic MRI and conventional qMRI (F=0.113, P=0.7537 and F=0.001, P=0.9737, respectively). For either method, there was no significant difference at different time points (F=0.613, P=0.4968 and F=1.162, P=0.3498, respectively).Conclusions The relaxation quantitative calculation results of T1 and T2 under the synthetic MRI are accurate, which is conducive to clinical application.
[Keywords] quantitative magnetic resonance imaging；synthetic magnetic resonance imaging；phantom verification；cerebral disease

LIU Yawen1, 2   NIU Haijun1, 2   YIN Hongxia3   ZHENG Zuofeng4   REN Pengling3   ZHANG Tingting1, 2, 3   ZHAO Pengfei3   LÜ Han3   WANG Zhenchang1, 2, 3  

1 School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China

2 Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing 100191, China

3 Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China

4 Department of Radiology, Beijing Chuiyangliu Hospital, Beijing 100022, China

Conflicts of interest   None.

ACKNOWLEDGMENTS National Natural Science Foundation of China (No. 61931013); Beijing Scholar 2015 (WANG Zhenchang).
Received  2021-11-23
Accepted  2022-03-21
DOI: 10.12015/issn.1674-8034.2022.04.016
Cite this article as: Liu YW, Niu HJ, Yin HX, et al. A comparative study on phantom verification of T1 and T2 relaxation values determined by synthetic MRI and conventional mapping methods[J]. Chin J Magn Reson Imaging, 2022, 13(4): 89-93. DOI:10.12015/issn.1674-8034.2022.04.016.

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