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• Clinical Article •
Preliminary study on the value of T2 mapping in predicting lymphovascular invasion of rectal cancer
LI Xiwei  LIU Ailian  CHEN Anliang  DONG Wan  SHEN Zhiwei  SONG Qingwei 

Cite this article as: Li XW, Liu AL, Chen AL, et al. Preliminary study on the value of T2 mapping in predicting lymphovascular invasion of rectal cancer[J]. Chin J Magn Reson Imaging, 2022, 13(6): 23-27. DOI:10.12015/issn.1674-8034.2022.06.005.


[Abstract] Objective To investigate the value of T2 mapping quantitative parameters in predicting lymphovascular invasion (LVI) and non-LVI of rectal cancer.Materials and methods A retrospective analysis of 34 cases with rectal cancer who underwent 3.0 T MRI scans in the First Affiliated Hospital of Dalian Medical University from October 2019 to November 2021 was divided into a LVI group (group A) of 13 cases and a non-LVI group (group B) of 21 cases. Scanning sequences include T1WI, T2WI, diffusion weighted imaging (DWI), and T2 mapping. Combined with the above sequence images, the lesions were located, and two observers placed three region of interest (ROIs) to measure the T2 value on the largest slice of the lesion displayed on the T2 mapping image. A Bland-Altman curve was used to test the agreement of the 2 observers' measurements. According to whether the data conformed to the normal distribution or not, independent samples t-test or Mann-Whitney U test was used to compare the difference of T2 value between rectal cancer group A and group B.Results T2 mapping parameters measured by the two observers were in consistent, and most of the scattered points in the Bland-Altman graph were evenly distributed between the +1.96 and -1.96 standard lines. The T2 values ​​of group A and group B were (77.15±6.95) ms and (87.06±7.55) ms, respectively. Group A was lower than group B, and the difference was statistically significant (P＜0.05); the area under the curve (AUC), threshold, sensitivity and specificity of T2 value in predicting LVI were 0.861, 83.19 ms, 84.62% and 76.19%, respectively.Conclusions T2 mapping has high value in predicting LVI of rectal cancer.
[Keywords] rectal cancer；lymphovascular invasion；magnetic resonance imaging；T2 mapping；prediction；distinguish；quantification

LI Xiwei1, 2   LIU Ailian1, 2*   CHEN Anliang1, 2   DONG Wan1, 2   SHEN Zhiwei3   SONG Qingwei1, 2  

1 Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian 116011, China

2 Dalian Medical Imaging Artificial Intelligence Engineering Technology Research Center, Dalian 116011, China

3 Department of Clinical Sciences, Philips Medical, Beijing 100016, China

Liu AL, E-mail: cjr.liuailian@vip.163.com

Conflicts of interest   None.

Received  2022-02-21
Accepted  2022-05-27
DOI: 10.12015/issn.1674-8034.2022.06.005
Cite this article as: Li XW, Liu AL, Chen AL, et al. Preliminary study on the value of T2 mapping in predicting lymphovascular invasion of rectal cancer[J]. Chin J Magn Reson Imaging, 2022, 13(6): 23-27. DOI:10.12015/issn.1674-8034.2022.06.005.

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