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Research progress of rt-fMRI-NF regulating amygdala activity and improving mood disorders
WANG Caiyun  QI Fei  WU Xiaoling  ZHOU Jing  ZOU Zhi  YAN Fengshan  DOU Shewei  LI Zhonglin  ZHU Zhimin  LI Yongli 

Cite this article as: WANG C Y, QI F, WU X L, et al. Research progress of rt-fMRI-NF regulating amygdala activity and improving mood disorders[J]. Chin J Magn Reson Imaging, 2023, 14(2): 149-152, 162. DOI:10.12015/issn.1674-8034.2023.02.026.


[Abstract] Real-time functional magnetic resonance imaging neurofeedback (rt-fMRI-NF) is an important advance in fMRI that changes brain function by regulating the activity of specific brain targets in subjects and thus affects the clinical behavior of subjects. The amygdala is a key brain region of the emotion regulation network, and the use of rt-fMRI-NF to regulate amygdala activity provides a novel bio-assisted treatment for the clinical treatment of mood disorders, which is a very promising technology. In this paper, by reviewing the emergence and basic principles of rt-fMRI-NF, the principle of regulating amygdala activity to improve mood disorders, the influencing factors of regulating the efficacy of amygdala activity, and the clinical application prospects and efficacy of regulating amygdala to improve mood disorders, this paper aims to provide a theoretical basis for rt-fMR-NF to regulate amygdala to improve mood disorders, and promote the wider development and application of rt-fMRI-NF as a clinical adjunct treatment for mental disorders.
[Keywords] real-time functional magnetic resonance imaging neurofeedback；magnetic resonance imaging；amygdala；depression；anxiety disorder；insomnia；posttraumatic stress disorder

WANG Caiyun1   QI Fei1   WU Xiaoling1   ZHOU Jing2   ZOU Zhi1   YAN Fengshan1   DOU Shewei1   LI Zhonglin1   ZHU Zhimin3   LI Yongli2*  

1 Department of Radiology, People's Hospital of Zhengzhou University/Henan Provincial People's Hospital, Henan Provincial Key Laboratory of Chronic Disease, Zhengzhou 450003, China

2 Department of Health Management, Henan Provincial People's Hospital, Henan Provincial Key Laboratory of Chronic Disease, Zhengzhou 450003, China

3 Department of Radiology, the Second Hospital of Yulin, Yulin 719000, China

*Correspondence to: Li YL, E-mail: shyliyongli@126.com

Conflicts of interest   None.

ACKNOWLEDGMENTS National Natural Science Foundation of China (No. 82071884); Henan Province Medical Science and Technology Research Project (No. LHGJ20200060); Henan Province Middle-aged and Young Health Science and Technology Innovation Talents Training Project (No. YXKC2020004).
Received  2022-07-27
Accepted  2023-01-17
DOI: 10.12015/issn.1674-8034.2023.02.026
Cite this article as: WANG C Y, QI F, WU X L, et al. Research progress of rt-fMRI-NF regulating amygdala activity and improving mood disorders[J]. Chin J Magn Reson Imaging, 2023, 14(2): 149-152, 162. DOI:10.12015/issn.1674-8034.2023.02.026.

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