Share:
Share this content in WeChat
X
Clinical Article
Correlation of corticospinal tract injury and the outcome of motor function after six months of intracerebral hemorrhage: quantitative evaluation with diffusion tensor tractography
LI Jing  LI Cheng  WANG Wei 

DOI:10.3969/j.issn.1674-8034.2010.01.006.


[Abstract] Objective: To investigate the predicting value by analyzing corticospinal tract (CST) injury to the motor function after intracerebral hemorrhage (ICH) with quantitative diffusion tensor tractography (DTT).Materials and Methods: Diffusion tensor imaging was performed in twenty-five acute ICH patients, whose hemorrhage involves basal ganglia, internal capsule or corona radiate. The affected side of CST was reconstructed with Volume-One 1.64 and diffusion Tensor Visualizer II(dTV II) software from Tokyo University. The relative remaining number of CST, which is as quantitative indicator, was calculated. Fugl-Meyer scoring was used to evaluate the prognosis.Results: The correlation coefficient (r value) between relative remaining number of CST and Fugl-Meyer score after six month of ICH is 0.879 (P<0.01).Conclusion: Quantitative DTT of CST could be used to predict the motor function in ICH patients.
[Keywords] Diffusion tensor tractography;Magnetic resonance imaging;Motor cortex;Cerebral hemorrhage

LI Jing Department of Radiology, the First Medicine College, Nanjing University of Chinese Medicine, Nanjing 210046, China

LI Cheng* Department of Imaging, the First People’s Hospital of Yangzhou, Yangzhou 225001, China

WANG Wei Department of Imaging, the First People’s Hospital of Yangzhou, Yangzhou 225001, China

*Correspondence to: Li C, E-mail: cjr.licheng@vip.163.com

Conflicts of interest   None.

Received  2009-12-23
Accepted  2010-01-15
DOI: 10.3969/j.issn.1674-8034.2010.01.006
DOI:10.3969/j.issn.1674-8034.2010.01.006.

[1]
Li J, Li C, Wang W, et al. Quantitative Measurement of Corticospinal Tracts by MR Fiber Tractography: A Reproducibility Study. Chinese Computed Medical Imaging, 2009, 15(1): 82-87.
[2]
Jang SH, Bai D, Son SM, et al. Motor outcome prediction using diffusion tensor tractography in pontine infarct. Ann Neurol, 2008, 64(4): 460-465.
[3]
Yoshioka H, Horikoshi T, Aoki S, et al. Diffusion tensor tractography predicts motor functional outcome in patients with spontaneous intracerebral hemorrhage. Neurosurgery, 2008, 62(1): 97-103; DOI: .
[4]
Jang SH, Ahn SH, Sakong J, Comparison of TMS and DTT for predicting motor outcome in intracerebral hemorrhage. J Neurol Sci. 2009 DOI: . [ DOI: ]
[5]
Stinear CM, Barber PA, Smale PR, et al. Functional potential in chronic stroke patients depends on corticospinal tract integrity. Brain, 2007, 130(Pt 1): 170-180.
[6]
Kim DG, Kim SH, Kim OL, et al. Long-term recovery of motor function in a quadriplegic patient with diffuse axonal injury and traumatic hemorrhage: a case report. NeuroRehabilitation, 2009, 25(2): 117-122.
[7]
Cho SH, Kim SH, Choi BY,et al. Motor outcome according to diffusion tensor tractography findings in the early stage of intracerebral hemorrhage. Neurosci Lett, 2007, 421(2): 142-146.
[8]
Konishi J, Yamada K, Kizu O, et al. MR tractography for the evaluation of functional recovery from lenticulostriate infarcts. Neurology, 2005, 64(1): 108-113.
[9]
Cho SH, Kim DG, Kim DS, et al. Motor outcome according to the integrity of the corticospinal tract determined by diffusion tensor tractography in the early stage of corona radiata infarct. Neurosci Lett, 2007, 16, 426(2): 123-127.
[10]
Nelles M, Giesekea J, Flackea S, et al. Diffusion Tensor Pyramidal Tractography in Patients With Anterior Choroidal Artery Infarcts. AJNR Am J Neuroradiol, 2008, 29(3): 488-493.
[11]
Liang Z, Zeng J, Zhang C, et al. Longitudinal investigations on the anterograde and retrograde degeneration in the pyramidal tract following pontine infarction with diffusion tensor imaging. Cerebrovasc Dis, 2008, 25(3): 209-216.
[12]
Jellison BJ, Field AS, Medow J, et al. Diffusion tensor imaging of cerebral white matter: a pictorial review of physics, fiber tract anatomy, and tumor imaging patterns. AJNR Am J Neuroradiol, 2004, 25(3): 356-369.

PREV Investigation of brain motor functional connectivity in ischemic stroke patients after rehabilitative treatment with resting-state functional MRI
NEXT Diffusion weighted MR imaging in differentiation of low grade gliomas
  



Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn