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• Clinical Article •
Susceptibility weighted imaging of reperfusion injury after mass cerebral infarction and correlation to clinical measures
ZHANG Qing  YANG Zhi-hong  WU Jian-lin  ZHANG Jing-wen  MIAO Yan-wei 

DOI:10.3969/j.issn.1674-8034.2010.01.008.


[Abstract] Objective: To evaluate susceptibility-weighted imaging (SWI) in the assessment of reperfusion injury after mass cerebral infarction and the correlation between imaging manifestations and clinical measures.Materials and Methods: Twenty-one patients with mass cerebral infarction were determined by the clinical and imaging manifestations. Patients with post-infarction hemorrhage were divided into mild, moderate and severe groups according to the volume of bleeding. The extent of micro-vessels around the infarction focus revealed in SWI was classified as 0-II degrees. The NIHSS scores of all the subjects were obtained and were correlated to SWI results.Results: Spontaneous post-infarction hemorrhage was observed in 16 subjects (76.2%), with 4 cases (25.0%) of severe bleeding, 5 cases (31.3%) of moderate bleeding, and 7 cases (43.8%) of mild bleeding, among which bleeding was found in 11 cases (68.8%) of sub-acute period. Severe hemorrhage positively correlated with NIHSS scores (rs=0.765, P=0.001). Micro-vessels around the lesions were found in 14 cases (66.7%). In 21 cases, 10 cases (47.6%) were II degree, 4 cases (19.0%) were I degree, 7 cases (33.3%) were 0 degree. The display degree of micro-vessels had no significant correlation with the NIHSS score (rs=0.408, P=0.066).Conclusion: SWI can make a sensitive, objective assessment of the reperfusion injury and collateral circulation after cerebral infarction, which is promisingly to be an effective evaluation method for the prognosis and treatment of the patients with infarction.
[Keywords] Susceptibility weighted imaging；Brain infarction；Reperfusion injury；Hemorrhage；Magnetic resonance imaging

ZHANG Qing Department of Radiology, the First Affiliated Hospital of Dalian Medical Univeresity, Dalian 116011, China

YANG Zhi-hong Department of Radiology, the First Affiliated Hospital of Dalian Medical Univeresity, Dalian 116011, China

WU Jian-lin* Department of Radiology, the First Affiliated Hospital of Dalian Medical Univeresity, Dalian 116011, China

ZHANG Jing-wen Department of Radiology, the First Affiliated Hospital of Dalian Medical Univeresity, Dalian 116011, China

MIAO Yan-wei Department of Radiology, the First Affiliated Hospital of Dalian Medical Univeresity, Dalian 116011, China

*Correspondence to: Wu JL, E-mail: cjr.wujianlin@vip.163.com

Conflicts of interest   None.

Received  2009-12-17
Accepted  2010-01-13
DOI: 10.3969/j.issn.1674-8034.2010.01.008
DOI:10.3969/j.issn.1674-8034.2010.01.008.

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