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• Clinical Article •
Initial study of susceptibility weighted imaging in brain masses
SHEN Jun-lin  ZHANG Hui  LIU Qi-wang  YANG Xiao-tang  QIAN Li-xia  ZHANG Suo-wang  LIANG Li  WANG Le 

DOI:10.3969/j.issn.1674-8034.2010.01.009.


[Abstract] Objective: To evaluate the value of susceptibility weighted imaging (SWI) in the diagnosis of brain masses.Materials and Methods: Forty-one patients with brain neoplasms underwent conventional MR T1WI, T2WI and SWI scanning. Thirty of them received both contrast enhanced T1WI and SWI (CE-T1WI and CE-SWI). Tumor visibility, edema, blood products, calcium, and vessels were observed respectively on SWI, the images of all sequences were scored from 0 to 3, according to their ability of depicting the observation projects above. Statistical analysis was conducted to compare the scores among these sequences.Results: Meningiomas and low-grade astrocytomas showed equisignal or mild hypersignal intensity; all recurrent meningiomas, high-grade astrocytomas and metastases in major displayed as mild low signal intensity. Venous vasculature both inside meningiomas and low-grade astrocytomas were relatively poorer than the recurrent ones, high-grade astrocytomas and metastases; perivenous showed arc compressed by the tumor in meningiomas, while displayed variously in other tumors. Calcium within the tumor appeared mainly in hypointense signal intensity surrounded by hyperintense signal ring on phase image, while blood product appeared conversely. Peri-edema displayed as high signal intensity. There was statistical difference of scores between SWI and conventional T1WI, T2WI in displaying blood products, calcium, and venous vasculature (P<0.01). There was no significant difference of scores between SWI and T2WI in displaying edema. Significant difference between the scores in detection of tumor visibility was found on the contrast enhanced sequences and non-contrast enhanced sequences (P<0.01).Conclusion: SWI sequence not only shows the general imaging features of brain masses but also detects venous vasculature, blood product and calcium within the tumor with superlative contrast. Different from conventional sequences, SWI shows unique details about internal architecture which is determined primarily by blood products. Phase image of SWI is helpful in differentiating blood product and calcium within the tumor.
[Keywords] Magnetic resonance imaging；Susceptibility weighted imaging；Brain neoplasms

SHEN Jun-lin Department of Radiology, the First Hospital of Shanxi Medical University, Taiyuan 030001, China

ZHANG Hui* Department of Radiology, the First Hospital of Shanxi Medical University, Taiyuan 030001, China

LIU Qi-wang Department of Radiology, the First Hospital of Shanxi Medical University, Taiyuan 030001, China

YANG Xiao-tang Department of Radiology, the First Hospital of Shanxi Medical University, Taiyuan 030001, China

QIAN Li-xia Department of Radiology, the First Hospital of Shanxi Medical University, Taiyuan 030001, China

ZHANG Suo-wang Department of Radiology, the First Hospital of Shanxi Medical University, Taiyuan 030001, China

LIANG Li Department of Radiology, the First Hospital of Shanxi Medical University, Taiyuan 030001, China

WANG Le Department of Radiology, the First Hospital of Shanxi Medical University, Taiyuan 030001, China

*Correspondence to: Zhang H, E-mail: zhanghui_mr@163.com

Conflicts of interest   None.

Received  2010-01-02
Accepted  2010-01-14
DOI: 10.3969/j.issn.1674-8034.2010.01.009
DOI:10.3969/j.issn.1674-8034.2010.01.009.

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