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• Clinical Article •
Diffusion tensor imaging in evaluation of benign prostatic hyperplasia: preliminary study
WANG Xi-zhen  NIU Qing-liang  SHEN Zhen  LIU Jin-gang  LI Hai-qing  WANG Bin 

DOI:10.3969/j.issn.1674-8034.2010.01.011.


[Abstract] Objective: To investigate the value of diffusion tensor imaging (DTI) in evaluating the structure of normal peripheral zone (PZ) and benign prostate hyperplasia (BPH).Materials and Methods: Twenty five patients with BPH were included in this study. DTI was performed using a 1.5 Tesla superconducting magnetic scanner (SIEMENS) equipped with a pelvic phased-array multi-coil. All data were transferred to SIEMENS Leonardo Workstation and different regions of interest (ROI) of PZ and BPH were drawn by a radiologist. Using the DTI card, the fractional anisotropy (FA) and mean apparent diffusion coefficients (ADC) of DTI were calculated and the corresponding index maps were produced.Results: The FA of PZ and BPH were 0.16±0.03 and 0.23±0.04, respectively. The FA of PZ were lower than that of BPH (P<0.05). The mean ADC value of BPH (1.37±0.27×10-3 mm2/s) was lower than that of PZ (1.85±0.34×10-3 mm2/s) (P<0.05). The directions, length and amount of BPH were different from those of PZ.Conclusion: DTI can be used to evaluate the three-dimensional architecture of PZ and BPH, which has the potential to provide useful information for the treatment of BPH.
[Keywords] Prostatic hyperplasia, benign；Magnetic resonance imaging, diffusion

WANG Xi-zhen Medical Imaging Center, Affiliated Hospital of Weifang Medical College, Weifang 261031, China

NIU Qing-liang Medical Imaging Center, Weifang Hospital of Traditional Chinese Medicine;, Weifang 261041, China

SHEN Zhen Medical Imaging Center, Affiliated Hospital of Weifang Medical College, Weifang 261031, China

LIU Jin-gang Medical Imaging Center, Affiliated Hospital of Weifang Medical College, Weifang 261031, China

LI Hai-qing Medical Imaging Center, Affiliated Hospital of Weifang Medical College, Weifang 261031, China

WANG Bin* Medical Imaging Center, Affiliated Hospital of Weifang Medical College, Weifang 261031, China

*Correspondence to: Wang B, E-mail: binwang001@yahoo.com.cn

Conflicts of interest   None.

Received  2009-12-10
Accepted  2010-01-12
DOI: 10.3969/j.issn.1674-8034.2010.01.011
DOI:10.3969/j.issn.1674-8034.2010.01.011.

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