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• Clinical Article •
Correlation between the severity of acute pancreatitis on MR imaging and liver function
TANG Wei  ZHANG Xiao-ming  HUANG Xiao-hua  XIAO Bo  ZENG Nan-lin  ZHAI Zhao-hua 

DOI:10.3969/j.issn.1674-8034.2010.01.012.


[Abstract] Objective: To investigate the correlation between the severity of acute pancreatitis (AP) on MR imaging and liver function.Materials and Methods: There were 64 patients with AP, all of whom had performed abdominal MR imaging. AP was categorized into types of edematous and necrotizing, and graded into mild (0-3 scores), moderate (4-6 scores) and severe (7-10 scores) according to the MR severity index (MRSI). The results of liver function test (ALT and AST) was noted and compared with the severity of AP on MRSI.Results: In the 64 patients with AP, 56 patients were edematous and 8 patients were necrotizing on MR imaging. The frequencies of ALT and AST elevated were both 100% in necrotizing AP, which were significantly larger than 55.4% (ALT) and 60.7% (AST) in edematous AP (P=0.014 and P=0.027, respectively). The frequencies of ALT and AST elevated were 48.8% and 53.5% in mild AP, 73.7% and 78.9% in moderate AP, and both 100% in severe AP, respectively. The frequency increasing of liver function abnormality tended to follow MRSI scores increasing. However, no significant difference for the frequencies can be seen among mild, moderate and severe AP.Conclusion: The necroses of AP on MR imaging may help to predict liver function abnormality in AP. However, MRSI could not be as index for predicting the abnormality of liver function in AP.
[Keywords] Pancreatitis, acute necrotizing；Magnetic resonance imaging；Severity of illness index；Liver failure

TANG Wei Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China

ZHANG Xiao-ming* Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China

HUANG Xiao-hua Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China

XIAO Bo Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China

ZENG Nan-lin Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China

ZHAI Zhao-hua Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong 637000, China

*Correspondence to: Zhang XM, E-mail: zhangxm@nsmc.edu.cn

Conflicts of interest   None.

Received  2010-01-06
Accepted  2010-01-15
DOI: 10.3969/j.issn.1674-8034.2010.01.012
DOI:10.3969/j.issn.1674-8034.2010.01.012.

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