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Clinical Article
Accuracy of MR imaging to identify the coronary artery plaque: comparison with intravascular ultrasound
ZHANG Zhao-qi  HE Yi  DAI Qin-yi  YU Wei  LI Meng 

DOI:10.3969/j.issn.1674-8034.2010.02.003.


[Abstract] Objective: To evaluate the ability of black blood coronary arterial wall MR imaging to identify the coronary artery plaque, using intravascular ultrasound (IVUS) as the golden standard.Materials and Methods: Eleven patients (mean age 61.8±9.7 years, 6 men and 5 women) who plan to do IVUS or had done IVUS examinations, but had not done percutaneous coronary intervention (PCI), underwent black-blood coronary wall MR imaging within 10 days before or after PCI respectively. All scans were performed on a 1.5T MR scanner. Cross-sectional coronary wall imaging was acquired using a 2D double-inversion-recovery, ECG-triggered, navigator-gated, fat-suppressed, Turbo-Spin-Echo (TSE) sequence on the lesion of coronary artery from the ostium to the middle segment continuously without gap. The vessel cross-sectional area (CSA), luminal CSA, maximal wall thickness, plaque burden, CNR [(SIvessel wall - SIperivascular area)/SDnoise) and SNR (SIvessel wall/SDnoise) were measured in each slice which were then compared with the IVUS images. IVUS were divided into 5 mm segments to compare side by side with MRI.Results: Nine coronary arteries and 37 slices from 9 patients were imaged and analyzed by both MRI and IVUS. Two patients were ruled out due to long examination time. Twenty of 37 slices were found plaques on both IVUS and MRI; the plaque burden, SNR, CNR in the coronary wall containing plaque were greater compared to the normal coronary wall (0.70±0.11 vs 0.58±0.14, 1.95±0.39 vs 1.48±0.21, 5.47±2.06 vs 2.99±0.78, respectively, P<0.05). There were good correlation between MRI and IVUS in vessel CSA, lumen CSA, and plaque burden.(13.66±4.52 vs 14.92±6.37, 4.62±2.23 vs 6.03±3.85, 0.63±0.13 vs 0.60±0.14, respectively, P<0.05).Conclusion: Coronary wall MRI can identify coronary plaque in proximal segments.
[Keywords] Magnetic resonance imaging;Coronary arteries;Vessel wall imaging;Black blood;Intravascular ultrasound

ZHANG Zhao-qi* Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

HE Yi Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

DAI Qin-yi Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

YU Wei Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

LI Meng Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

*Correspondence to: Zhang ZQ, E-mail: zhaoqi5000@vip.sohu.com

Conflicts of interest   None.

Received  2010-02-20
Accepted  2010-03-10
DOI: 10.3969/j.issn.1674-8034.2010.02.003
DOI:10.3969/j.issn.1674-8034.2010.02.003.

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