Share：
Share this content in WeChat
X
[Chinese][PDF]74085
• Clinical Article •
Accuracy of MR imaging to identify the coronary artery plaque: comparison with intravascular ultrasound
ZHANG Zhao-qi  HE Yi  DAI Qin-yi  YU Wei  LI Meng 

DOI:10.3969/j.issn.1674-8034.2010.02.003.


[Abstract] Objective: To evaluate the ability of black blood coronary arterial wall MR imaging to identify the coronary artery plaque, using intravascular ultrasound (IVUS) as the golden standard.Materials and Methods: Eleven patients (mean age 61.8±9.7 years, 6 men and 5 women) who plan to do IVUS or had done IVUS examinations, but had not done percutaneous coronary intervention (PCI), underwent black-blood coronary wall MR imaging within 10 days before or after PCI respectively. All scans were performed on a 1.5T MR scanner. Cross-sectional coronary wall imaging was acquired using a 2D double-inversion-recovery, ECG-triggered, navigator-gated, fat-suppressed, Turbo-Spin-Echo (TSE) sequence on the lesion of coronary artery from the ostium to the middle segment continuously without gap. The vessel cross-sectional area (CSA), luminal CSA, maximal wall thickness, plaque burden, CNR [(SIvessel wall - SIperivascular area)/SDnoise) and SNR (SIvessel wall/SDnoise) were measured in each slice which were then compared with the IVUS images. IVUS were divided into 5 mm segments to compare side by side with MRI.Results: Nine coronary arteries and 37 slices from 9 patients were imaged and analyzed by both MRI and IVUS. Two patients were ruled out due to long examination time. Twenty of 37 slices were found plaques on both IVUS and MRI; the plaque burden, SNR, CNR in the coronary wall containing plaque were greater compared to the normal coronary wall (0.70±0.11 vs 0.58±0.14, 1.95±0.39 vs 1.48±0.21, 5.47±2.06 vs 2.99±0.78, respectively, P<0.05). There were good correlation between MRI and IVUS in vessel CSA, lumen CSA, and plaque burden.(13.66±4.52 vs 14.92±6.37, 4.62±2.23 vs 6.03±3.85, 0.63±0.13 vs 0.60±0.14, respectively, P<0.05).Conclusion: Coronary wall MRI can identify coronary plaque in proximal segments.
[Keywords] Magnetic resonance imaging；Coronary arteries；Vessel wall imaging；Black blood；Intravascular ultrasound

ZHANG Zhao-qi* Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

HE Yi Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

DAI Qin-yi Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

YU Wei Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

LI Meng Department of Radiology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

*Correspondence to: Zhang ZQ, E-mail: zhaoqi5000@vip.sohu.com

Conflicts of interest   None.

Received  2010-02-20
Accepted  2010-03-10
DOI: 10.3969/j.issn.1674-8034.2010.02.003
DOI:10.3969/j.issn.1674-8034.2010.02.003.

[1]
Libby P. Coronary artery injury and the biology of atherosclerosis: inflammation, thrombosis, and stabilization. Am J Cardiol, 2000, 86:3J-8J.
[2]
Shea S, et al. Proc ISMRM 2007, 15: 2475.
[3]
Leber AW, Knez A, Becker A, et al. Accuracy of multidetector spiral computed tomography in identifying and differentiating the composition of coronary atherosclerotic plaques: a comparative study with intracoronary ultrasound. J Am Coll Cardiol, 2004, 43:1241-1247.
[4]
Leber AW, Becker A, Knez A, et al. Accuracy of 64-slice computed tomography to classify and quantify plaque volumes in the proximal coronary system: comparative study using intravascular ultrasound. J Am Coll Cardiol, 2006, 47:672-677.
[5]
Mollet NR, Cademartiri F, van Mieghem CA, et al. High-resolution spiral computed tomography coronary angiography in patients referred for diagnostic conventional coronary angiography. Circulation, 2005, 112: 2318-2323.
[6]
Dewey M, Teige F, Schnapauff D, et al. Combination of free-breathing and breathhold steady-state free precession magnetic resonance angiography for detection of coronary artery stenosis. J Magn Reson Imaging, 2006, 23: 674-681.
[7]
Fayad ZA, Fuster V, Fallon JT, et al. Noninvasive in vivo human coronary artery lumen and wall imaging using black-blood magnetic resonance imaging. Circulation, 2000, 102: 506-510.
[8]
Kim WY, Stuber M, Bornert P, et al. Three-dimensional black-blood cardiac magnetic resonance coronary vessel wall imaging detects positive arterial remodeling in patients with nonsignificant coronary artery disease. Circulation, 2002, 106: 296-299.
[9]
Miao C, Chen S, Macedo R, et al. Positive remodeling of the coronary arteries detected by magnetic resonance imaging in an asymptomatic population MESA (Multi-Ethnic Study of Atherosclerosis). J Am Coll Cardiol, 2009, 53: 1708-1715.
[10]
Kim WY, Astrup AS, Stuber M, et al. Subclinical coronary and aortic atherosclerosis detected by magnetic resonance imaging in type 1 diabetes with and without diabetic nephropathy. Circulation, 2007, 115: 228-235.
[11]
Te Boekhorst BC, Cramer MJ, Pasterkamp G, et al. Recent developments and new perspectives on imaging of atherosclerotic plaque: role of anatomical, cellular and molecular MRI Part I and II. Int J Cardiovasc Imaging, 2010 DOI: . [ DOI: ]
[12]
Wasserman BA, Astor BC, Sharrett AR, Swingen C, et al. MRI measurements of carotid plaque in the atherosclerosis risk in communities (ARIC) study: methods, reliability and descriptive statistics. J Magn Reson Imaging, 2010, 31: 406-415.

PREV Three-dimensional high resolution venography using susceptibility weighted imaging at 7T
NEXT MR imaging findings in noncompaction of ventricular myocardium
  


LINK


Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn