Share:
Share this content in WeChat
X
Clinical Article
Clinical value of assessing the activity of rheumatoid arthritis using revised MRI scoring system
LIU Xia  LI Xu-bin  HONG Nan  DU Xiang-ke 

DOI:10.3969/j.issn.1674-8034.2010.02.006.


[Abstract] Objective: To investigate the clinical value of assessing the activity of rheumatoid arthritis using revised MRI scoring system.Materials and Methods: MR images of both wrists and the 2nd to 5th metacarpophalangeal joints of 77 patients with RA were analyzed. MRI scores of each patient were acquired using a revised OMERACT RAMRIS Scoring System, which was based on initial OMERACT RAMRIS Scoring System and added the scores of the proximal interphalangeal joints, distal interphalangeal joints and tenosynovistis.The intra- and inter-reader reliability of MRI scoring system was assessed. The relationships between MRI score of each sign, between MRI score and clinical data were analyzed respectively.Results: There was a significant correlation between MRI total score and CRP (r= 0.322, P=0.009), ESR (r=0.406, P=0.001), between bone edema score, tenosynovitis score and CRP (r=0.348 and 0.414, P=0.017 and 0.004), between tenosynovitis score and the number of pain joints (r=0.329, P=0.013), between synovitis score and bone erosion score (r=0.542, P=0.000), bone edema score (r=0.365, P=0.001), tenosynovits score (r=0.610, P=0.000), between bone erosion score and bone edema score (r=0.543, P=0.000), tenosynovitis score (r=0.430, P=0.000), between bone edema score and the tenosynovitis score (r=0.671, P=0.000).Conclusion: The revised MRI scoring system can be used to assess the activity of RA semi-quantitatively and play an important role in clinical study.
[Keywords] Arthritis, rheumatoid;Wrist joint;Magnetic resonance imaging

LIU Xia* Department of Radiology, Peking University People’s Hospital, Beijing 100044, China

LI Xu-bin Department of Radiology, Peking University People’s Hospital, Beijing 100044, China

HONG Nan Department of Radiology, Peking University People’s Hospital, Beijing 100044, China

DU Xiang-ke Department of Radiology, Peking University People’s Hospital, Beijing 100044, China

*Correspondence to: Liu X, E-mail: iamliuxia1@126.com

Conflicts of interest   None.

Received  2010-01-18
Accepted  2010-03-01
DOI: 10.3969/j.issn.1674-8034.2010.02.006
DOI:10.3969/j.issn.1674-8034.2010.02.006.

[1]
Ejbjerg B, McQueen F, Lassere M, et al. The EULAR-OMERACT rheumatoid arthritis MRI reference image atlas: the wrist joint. Ann Rheum Dis, 2005, 64 (Suppl 1): i23-47.
[2]
Conaghan P, Bird P, Ejbjerg B, et al. The EULAR-OMERACT rheumatoid arthritis MRI reference image atlas: the metacarpophalangeal joints. Ann Rheum Dis, 2005, 64(Suppl 1): i11-21.
[3]
Boers M, Brooks P, Strand CV, et al. The OMERACT filter for Outcome Measures in Rheumatology. J Rheumatol, 1998, 25: 198-199.
[4]
Haavardsholm EA, Kvan NP, Ostergaard M, et al. Reliability of the OMERACT rheumatoid arthritis MRI Score (RAMRIS) in a multi-reader longitudinal setting. Arthritis Rheum, 2004, 50(Suppl 9): S457-S458.
[5]
Bird P, Kirkham B, Portek I, et al. Documenting damage progression in a two-year longitudinal study of rheumatoid arthritis patients with established disease (the DAMAGE study cohort): is there an advantage in the use of magnetic resonance imaging as compared with plain radiography? Arthritis Rheum, 2004, 50: 1383-1389.
[6]
Gianluca V, Calogero F, Paola E, et al. Tendon involvement in rheumatoid arthritis of the wrist: MRI findings. Skeletal Radiol, 2001, 30: 138-143.
[7]
Ostergaard M, Duer A, Nielsen H, et al. Magnetic resonance imaging for accelerated assessment of drug effect and prediction of subsequent radiographic progression in rheumatoid arthritis: a study of patients receiving combined anakinra and methotrexate treatment. Ann Rheum Dis, 2005, 64: 1503-1506.

PREV Effects of neoadjuvant chemoradiotherapy prior to surgery on rectal cancer assessing by DCE-MRI
NEXT MRI manifestations of "dural tail sign" in meningioma and its related pathology
  



Tel & Fax: +8610-67113815    E-mail: editor@cjmri.cn